|
|
CSNK2A1 |
casein kinase 2 alpha 1 |
- Synthesis of PC
- WNT mediated activation of DVL
- Condensation of Prometaphase Chromosomes
- Signal transduction by L1
- Regulation of TP53 Activity through Phosphorylation
- Cooperation of PDCL (PhLP1) and TRiC/CCT in G-protein beta folding
- Receptor Mediated Mitophagy
- RUNX1 interacts with co-factors whose precise effect on RUNX1 targets is not known
- Regulation of PTEN stability and activity
|
- ATP
- (5-hydroxyindolo[1,2-a]quinazolin-7-yl)acetic acid
- 1,8-Di-Hydroxy-4-Nitro-Xanthen-9-One
- Resveratrol
- 1,8-Di-Hydroxy-4-Nitro-Anthraquinone
- Benzamidine
- 5,8-Di-Amino-1,4-Dihydroxy-Anthraquinone
- Quercetin
- Phosphoaminophosphonic Acid-Adenylate Ester
- Tetrabromo-2-Benzotriazole
- DIMETHYL-(4,5,6,7-TETRABROMO-1H-BENZOIMIDAZOL-2-YL)-AMINE
- S-METHYL-4,5,6,7-TETRABROMO-BENZIMIDAZOLE
- N1,N2-ETHYLENE-2-METHYLAMINO-4,5,6,7-TETRABROMO-BENZIMIDAZOLE
- Emodin
- 3,8-DIBROMO-7-HYDROXY-4-METHYL-2H-CHROMEN-2-ONE
- 19-(cyclopropylamino)-4,6,7,15-tetrahydro-5H-16,1-(azenometheno)-10,14-(metheno)pyrazolo[4,3-o][1,3,9]triazacyclohexadecin-8(9H)-one
- N,N'-DIPHENYLPYRAZOLO[1,5-A][1,3,5]TRIAZINE-2,4-DIAMINE
- 4-(2-(1H-IMIDAZOL-4-YL)ETHYLAMINO)-2-(PHENYLAMINO)PYRAZOLO[1,5-A][1,3,5]TRIAZINE-8-CARBONITRILE
- 2-(CYCLOHEXYLMETHYLAMINO)-4-(PHENYLAMINO)PYRAZOLO[1,5-A][1,3,5]TRIAZINE-8-CARBONITRILE
- 2-(4-CHLOROBENZYLAMINO)-4-(PHENYLAMINO)PYRAZOLO[1,5-A][1,3,5]TRIAZINE-8-CARBONITRILE
- 2-(4-ETHYLPIPERAZIN-1-YL)-4-(PHENYLAMINO)PYRAZOLO[1,5-A][1,3,5]TRIAZINE-8-CARBONITRILE
- N-(3-(8-CYANO-4-(PHENYLAMINO)PYRAZOLO[1,5-A][1,3,5]TRIAZIN-2-YLAMINO)PHENYL)ACETAMIDE
- Dichlororibofuranosylbenzimidazole
- Quinalizarin
- Ellagic acid
- Fostamatinib
|
|
|
|
CWF19L2 |
CWF19 like cell cycle control factor 2 |
|
|
|
|
|
CYFIP2 |
cytoplasmic FMR1 interacting protein 2 |
- Regulation of actin dynamics for phagocytic cup formation
- Regulation of actin dynamics for phagocytic cup formation
- VEGFA-VEGFR2 Pathway
- RHO GTPases Activate WASPs and WAVEs
- RHO GTPases Activate WASPs and WAVEs
- FCGR3A-mediated phagocytosis
- FCGR3A-mediated phagocytosis
|
|
|
|
|
DHX15 |
DEAH-box helicase 15 |
- mRNA Splicing - Major Pathway
|
|
|
|
|
ELOA |
elongin A |
- Formation of RNA Pol II elongation complex
- Formation of HIV elongation complex in the absence of HIV Tat
- Formation of HIV-1 elongation complex containing HIV-1 Tat
- Pausing and recovery of Tat-mediated HIV elongation
- Tat-mediated HIV elongation arrest and recovery
- Tat-mediated elongation of the HIV-1 transcript
- HIV elongation arrest and recovery
- Pausing and recovery of HIV elongation
- RNA Polymerase II Pre-transcription Events
- TP53 Regulates Transcription of DNA Repair Genes
- RNA Polymerase II Transcription Elongation
|
|
|
|
|
ERCC6 |
ERCC excision repair 6, chromatin remodeling factor |
- ERCC6 (CSB) and EHMT2 (G9a) positively regulate rRNA expression
- B-WICH complex positively regulates rRNA expression
- Formation of TC-NER Pre-Incision Complex
- Transcription-Coupled Nucleotide Excision Repair (TC-NER)
- Dual incision in TC-NER
- Gap-filling DNA repair synthesis and ligation in TC-NER
- RNA Polymerase I Transcription Initiation
|
|
- Disorders of nucleotide excision repair, including: Xeroderma pigmentosum (XP); Cockayne syndrome (CS); UV-sensitive syndrome (UVS); Trichothiodystrophy (TTD); Cerebro-oculo-facio-skeletal syndrome (COFS); XFE progeroid syndrome
- Cockayne syndrome
- Macular degeneration, including: Age-related macular degeneration (ARMD); Patterned dystrophy of retinal pigment epithelium (PDREP); Retinal macular dystrophy 2 (MCDR2); X-linked atrophic macular degeneration (MDXLA)
|
|
|
ERG28 |
ergosterol biosynthesis 28 homolog |
|
|
|
|
|
ESCO2 |
establishment of sister chromatid cohesion N-acetyltransferase 2 |
- Establishment of Sister Chromatid Cohesion
|
|
- ESCO2-related disorders, including: Roberts syndrome; SC phocomelia syndrome
|
|
|
FAM161A |
FAM161 centrosomal protein A |
|
|
- Retinitis pigmentosa (RP)
|
|
|
FAM90A1 |
family with sequence similarity 90 member A1 |
|
|
|
|
|
FBXO4 |
F-box protein 4 |
- Association of TriC/CCT with target proteins during biosynthesis
- Neddylation
- Antigen processing: Ubiquitination & Proteasome degradation
|
|
|
|
|
FMR1 |
FMRP translational regulator 1 |
|
|
- Premature ovarian failure
- Fragile X Syndrome, including: Fragile X Syndrome (FXS); Fragile X tremor/ataxia syndrome (FXTAS)
|
|
|
FXR2 |
FMR1 autosomal homolog 2 |
|
|
|
|
|
GBP2 |
guanylate binding protein 2 |
- Interferon gamma signaling
- Interferon alpha/beta signaling
|
|
|
|
|
HSPB1 |
heat shock protein family B (small) member 1 |
- VEGFA-VEGFR2 Pathway
- AUF1 (hnRNP D0) binds and destabilizes mRNA
- MAPK6/MAPK4 signaling
- Extra-nuclear estrogen signaling
|
- Apatorsen
- Artenimol
- Phenethyl Isothiocyanate
|
- Distal hereditary motor neuropathies (dHMN)
|
|
|
KIF9 |
kinesin family member 9 |
- COPI-dependent Golgi-to-ER retrograde traffic
- Kinesins
- Kinesins
|
|
|
|
|
LNX1 |
ligand of numb-protein X 1 |
- Antigen processing: Ubiquitination & Proteasome degradation
|
|
|
|
|
LRIF1 |
ligand dependent nuclear receptor interacting factor 1 |
|
|
|
|
|
LUC7L2 |
LUC7 like 2, pre-mRNA splicing factor |
|
|
|
|
|
MAGOH |
mago homolog, exon junction complex subunit |
- Transport of Mature mRNA derived from an Intron-Containing Transcript
- mRNA Splicing - Major Pathway
- mRNA 3'-end processing
- RNA Polymerase II Transcription Termination
- Regulation of expression of SLITs and ROBOs
- Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)
|
|
|