Search Results for: EXOSC2

29 interactions involving EXOSC2 - exosome component 2 found:

Sort by: Symbol Number of Pathways Number of Drugs Number of Diseases
Novel Interactant Symbol Name
Associated Pathways
Binding Drugs
Associated Diseases
MRPL48 mitochondrial ribosomal protein L48
  • Mitochondrial translation initiation
  • Mitochondrial translation elongation
  • Mitochondrial translation elongation
  • Mitochondrial translation termination
MTREX Mtr4 exosome RNA helicase
  • Major pathway of rRNA processing in the nucleolus and cytosol
  • mRNA Splicing - Major Pathway
PALS2 protein associated with LIN7 2, MAGUK family member
PTEN phosphatase and tensin homolog
  • Synthesis of PIPs at the plasma membrane
  • Synthesis of IP3 and IP4 in the cytosol
  • Negative regulation of the PI3K/AKT network
  • Downstream TCR signaling
  • TP53 Regulates Metabolic Genes
  • PTEN Loss of Function in Cancer
  • Ub-specific processing proteases
  • Ovarian tumor domain proteases
  • Regulation of PTEN mRNA translation
  • Regulation of PTEN localization
  • Regulation of PTEN stability and activity
  • Transcriptional Regulation by MECP2
  • Phosphatidylethanolamine
  • Vulvar cancer
  • Prostate cancer
  • Endometrial Cancer
  • Glioma
  • Small cell lung cancer
  • Breast cancer
  • Hepatocellular carcinoma
  • Malignant melanoma
RNF8 ring finger protein 8
  • Recruitment and ATM-mediated phosphorylation of repair and signaling proteins at DNA double strand breaks
  • Nonhomologous End-Joining (NHEJ)
  • Processing of DNA double-strand break ends
  • G2/M DNA damage checkpoint
SBK3 SH3 domain binding kinase family member 3
  • Fostamatinib
ST6GALNAC1 ST6 N-acetylgalactosaminide alpha-2,6-sialyltransferase 1
  • Sialic acid metabolism
UPF1 UPF1 RNA helicase and ATPase
  • Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)
  • Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)
ZNF408 zinc finger protein 408

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