Search Results for: TLE5

Novel Interactant Symbol Name
Associated Pathways
Binding Drugs
Associated Diseases
RHOXF2 Rhox homeobox family member 2
RIBC1 RIB43A domain with coiled-coils 1
RIMBP3 RIMS binding protein 3
RIPPLY1 ripply transcriptional repressor 1
RNF31 ring finger protein 31
  • Regulation of TNFR1 signaling
  • TNFR1-induced NFkappaB signaling pathway
RORB RAR related orphan receptor B
RPL18A ribosomal protein L18a
  • L13a-mediated translational silencing of Ceruloplasmin expression
  • Peptide chain elongation
  • SRP-dependent cotranslational protein targeting to membrane
  • SRP-dependent cotranslational protein targeting to membrane
  • Viral mRNA Translation
  • Selenocysteine synthesis
  • Major pathway of rRNA processing in the nucleolus and cytosol
  • Formation of a pool of free 40S subunits
  • GTP hydrolysis and joining of the 60S ribosomal subunit
  • Eukaryotic Translation Termination
  • Regulation of expression of SLITs and ROBOs
  • Response of EIF2AK4 (GCN2) to amino acid deficiency
  • Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)
  • Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)
RUNX1 RUNX family transcription factor 1
  • Pre-NOTCH Transcription and Translation
  • Organic cation transport
  • RUNX1 and FOXP3 control the development of regulatory T lymphocytes (Tregs)
  • RUNX1 regulates estrogen receptor mediated transcription
  • Regulation of RUNX1 Expression and Activity
  • Regulation of RUNX1 Expression and Activity
  • RUNX1 regulates expression of components of tight junctions
  • RUNX1 regulates genes involved in megakaryocyte differentiation and platelet function
  • RUNX1 regulates transcription of genes involved in differentiation of HSCs
  • RUNX1 regulates transcription of genes involved in differentiation of HSCs
  • RUNX1 regulates transcription of genes involved in differentiation of keratinocytes
  • RUNX1 regulates transcription of genes involved in differentiation of keratinocytes
  • RUNX1 interacts with co-factors whose precise effect on RUNX1 targets is not known
  • RUNX1 regulates transcription of genes involved in BCR signaling
  • RUNX1 regulates transcription of genes involved in differentiation of myeloid cells
  • RUNX1 regulates transcription of genes involved in interleukin signaling
  • RUNX1 regulates transcription of genes involved in WNT signaling
  • RUNX2 regulates genes involved in differentiation of myeloid cells
  • RUNX3 regulates p14-ARF
  • Estrogen-dependent gene expression
  • Transcriptional regulation of granulopoiesis
  • Chronic myeloid leukemia (CML)
  • Thrombocytopenia (THC); Familial platelet disorder with associated myeloid malignancy (FPDMM)
  • Acute myeloid leukemia (AML)
  • Acute lymphoblastic leukemia (ALL) (precursor B lymphoblastic leukemia)
RUSC1 RUN and SH3 domain containing 1
SAT1 spermidine/spermine N1-acetyltransferase 1
  • Interconversion of polyamines
  • N-ethyl-N-[3-(propylamino)propyl]propane-1,3-diamine
  • Keratosis follicularis spinulosa decalvans
SCNM1 sodium channel modifier 1
SDCBP syndecan binding protein
  • Ephrin signaling
  • Neurofascin interactions
  • RIPK1-mediated regulated necrosis
  • Regulation of necroptotic cell death
  • Neutrophil degranulation
SERTAD3 SERTA domain containing 3
SET SET nuclear proto-oncogene
  • Condensation of Prophase Chromosomes
  • HuR (ELAVL1) binds and stabilizes mRNA
SF3B4 splicing factor 3b subunit 4
  • mRNA Splicing - Major Pathway
  • mRNA Splicing - Minor Pathway
SH2B2 SH2B adaptor protein 2
  • Regulation of KIT signaling
  • Factors involved in megakaryocyte development and platelet production
SH3GL3 SH3 domain containing GRB2 like 3, endophilin A3
  • EGFR downregulation
  • Negative regulation of MET activity
  • Cargo recognition for clathrin-mediated endocytosis
  • Clathrin-mediated endocytosis
  • InlB-mediated entry of Listeria monocytogenes into host cell
  • NGF-stimulated transcription
SHFL shiftless antiviral inhibitor of ribosomal frameshifting
SHISA6 shisa family member 6
SIX1 SIX homeobox 1
  • Contiguous gene deletion syndrome involving EYA1, including: Oto-facio-cervical syndrome (OFC); Branchiootic syndrome 1 (BOS1); Branchio-oto-renal syndrome (BOR)

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