TLE5 - New-wiki

Interactant Symbol	Name	Associated Pathways Hide	Associated Diseases Hide
OSGIN1	oxidative stress induced growth inhibitor 1
OXER1	oxoeicosanoid receptor 1	Eicosanoid ligand-binding receptors G alpha (i) signalling events
P4HA3	prolyl 4-hydroxylase subunit alpha 3	Collagen biosynthesis and modifying enzymes
PARVG	parvin gamma
PATZ1	POZ/BTB and AT hook containing zinc finger 1
PAX8	paired box 8		Thyroid cancer Congenital nongoitrous hypothyroidism (CHNG)
PAX9	paired box 9		Tooth agenesis; Hypodontia
PCBP1	poly(rC) binding protein 1	mRNA Splicing - Major Pathway Processing of Capped Intron-Containing Pre-mRNA
PCSK5	proprotein convertase subtilisin/kexin type 5	NGF processing Assembly of active LPL and LIPC lipase complexes
PFDN5	prefoldin subunit 5	Prefoldin mediated transfer of substrate to CCT/TriC
PHF1	PHD finger protein 1	PRC2 methylates histones and DNA
PICK1	protein interacting with PRKCA 1	Cell surface interactions at the vascular wall Trafficking of GluR2-containing AMPA receptors
PITX1	paired like homeodomain 1		Congenital clubfoot; Congenital talipes equinovarus
PITX2	paired like homeodomain 2	TFAP2 (AP-2) family regulates transcription of other transcription factors	Axenfeld-Rieger syndrome (ARS)
PLAGL1	PLAG1 like zinc finger 1	TP53 regulates transcription of additional cell cycle genes whose exact role in the p53 pathway remain uncertain	Transient neonatal diabetes mellitus (TNDM)
POLR1C	RNA polymerase I and III subunit C	Cytosolic sensors of pathogen-associated DNA NoRC negatively regulates rRNA expression B-WICH complex positively regulates rRNA expression RNA Polymerase I Transcription Initiation RNA Polymerase I Transcription Initiation RNA Polymerase I Promoter Escape RNA Polymerase III Chain Elongation RNA Polymerase I Transcription Termination RNA Polymerase III Transcription Termination RNA Polymerase III Abortive And Retractive Initiation RNA Polymerase III Transcription Initiation From Type 1 Promoter RNA Polymerase III Transcription Initiation From Type 1 Promoter RNA Polymerase III Transcription Initiation From Type 2 Promoter RNA Polymerase III Transcription Initiation From Type 2 Promoter RNA Polymerase III Transcription Initiation From Type 3 Promoter RNA Polymerase III Transcription Initiation From Type 3 Promoter	Treacher Collins syndrome
POU2F1	POU class 2 homeobox 1	Interleukin-4 and Interleukin-13 signaling RNA polymerase II transcribes snRNA genes RNA polymerase II transcribes snRNA genes RNA Polymerase III Abortive And Retractive Initiation RNA Polymerase III Transcription Initiation From Type 3 Promoter RNA Polymerase III Transcription Initiation From Type 3 Promoter Estrogen-dependent gene expression
PPP1R16A	protein phosphatase 1 regulatory subunit 16A
PPP1R16B	protein phosphatase 1 regulatory subunit 16B
PRDM1	PR/SET domain 1	Regulation of TP53 Expression

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