PRKACA - New-wiki

Interactant Symbol	Name	Associated Pathways Hide	Binding Drugs Hide	Associated Diseases Hide
STUB1	STIP1 homology and U-box containing protein 1	Downregulation of TGF-beta receptor signaling RIPK1-mediated regulated necrosis Regulation of necroptotic cell death Downregulation of ERBB2 signaling Regulation of RUNX2 expression and activity Regulation of PTEN stability and activity Antigen processing: Ubiquitination & Proteasome degradation
SYN1	synapsin I	Serotonin Neurotransmitter Release Cycle Dopamine Neurotransmitter Release Cycle	Adenosine 5'-[gamma-thio]triphosphate	Syndromic X-linked mental retardation with epilepsy or seizures, including: West syndrome (WS); Partington syndrome (PRTS); Proud syndrome (ACCAG); XMR and epilepsy (XMRE); MRXHF1; XMR OPHN1-related (MRXSO) ; XELBD; XMR, Christianson type (MRXSC); Creatine deficiency syndrome (XL-CDS); Renpenning syndrome (RENS1); Epilepsy and mental retardation limited to females (EFMR); Periventricular nodular heterotopia (PVNH); Hydrocephalus (XLH); XMR, JARID1C related (MRXSJ); Boerjeson-Forssman syndrome (BFLS); CK syndrome (CKS)
SYN2	synapsin II	Serotonin Neurotransmitter Release Cycle Dopamine Neurotransmitter Release Cycle
TH	tyrosine hydroxylase	Catecholamine biosynthesis	Phenylalanine Tyrosine Sapropterin Metyrosine 3-Tyrosine L-erythro-7,8-dihydrobiopterin	Primary torsion dystonia (PTD)
THOP1	thimet oligopeptidase 1	Antigen processing: Ubiquitination & Proteasome degradation
TNP1	transition protein 1
TNP2	transition protein 2
TPH1	tryptophan hydroxylase 1	Serotonin and melatonin biosynthesis NGF-stimulated transcription	Sapropterin LX1031 Telotristat ethyl
TRIM55	tripartite motif containing 55
TRIM63	tripartite motif containing 63	FOXO-mediated transcription of oxidative stress, metabolic and neuronal genes Antigen processing: Ubiquitination & Proteasome degradation
TRIP10	thyroid hormone receptor interactor 10	Rho GTPase cycle Clathrin-mediated endocytosis
UBE3A	ubiquitin protein ligase E3A	Antigen processing: Ubiquitination & Proteasome degradation		Prader-Willi and Angelman syndromes, including: Angelman syndrome (AS); Prader-Willi syndrome (PWS)
UHRF1	ubiquitin like with PHD and ring finger domains 1	DNA methylation
USP20	ubiquitin specific peptidase 20	Ub-specific processing proteases
VASP	vasodilator stimulated phosphoprotein	Generation of second messenger molecules Signaling by ROBO receptors Signaling by ROBO receptors Cell-extracellular matrix interactions
VIM	vimentin	Caspase-mediated cleavage of cytoskeletal proteins Striated Muscle Contraction Interleukin-4 and Interleukin-13 signaling Chaperone Mediated Autophagy Late endosomal microautophagy Aggrephagy	Artenimol Phenethyl Isothiocyanate
VTN	vitronectin	Molecules associated with elastic fibres Integrin cell surface interactions Syndecan interactions ECM proteoglycans ECM proteoglycans Regulation of Complement cascade	Abciximab Zinc Copper Zinc acetate Zinc chloride Zinc sulfate, unspecified form
WT1	WT1 transcription factor	Transcriptional regulation of testis differentiation		Nephrotic syndrome and focal segmental glomerulosclerosis 46,XY disorders of sex development (Disorders of gonadal development), including: Gonadal agenesis; Complete and partial gonadal dysgenesis; Testis regression; Ovotesticular DSD
YWHAZ	tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein zeta	Activation of BAD and translocation to mitochondria Translocation of SLC2A4 (GLUT4) to the plasma membrane Deactivation of the beta-catenin transactivating complex Rap1 signalling GP1b-IX-V activation signalling KSRP (KHSRP) binds and destabilizes mRNA Interleukin-3, Interleukin-5 and GM-CSF signaling RHO GTPases activate PKNs TP53 Regulates Metabolic Genes Chk1/Chk2(Cds1) mediated inactivation of Cyclin B:Cdk1 complex NOTCH4 Activation and Transmission of Signal to the Nucleus Negative regulation of NOTCH4 signaling Regulation of localization of FOXO transcription factors	Phenethyl Isothiocyanate

Search Results for: PRKACA