PMPCB - New-wiki

Novel	Interactant Symbol	Name	Associated Pathways Hide	Binding Drugs Hide	Associated Diseases Hide
Novel	AP4M1	adaptor related protein complex 4 subunit mu 1	Lysosome Vesicle Biogenesis		Cerebral palsy
Novel	ARPC1B	actin related protein 2/3 complex subunit 1B	Regulation of actin dynamics for phagocytic cup formation Regulation of actin dynamics for phagocytic cup formation EPHB-mediated forward signaling RHO GTPases Activate WASPs and WAVEs RHO GTPases Activate WASPs and WAVEs FCGR3A-mediated phagocytosis FCGR3A-mediated phagocytosis	N-[2-(2-methyl-1H-indol-3-yl)ethyl]thiophene-2-carboxamide (2S)-2-(3-bromophenyl)-3-(5-chloro-2-hydroxyphenyl)-1,3-thiazolidin-4-one
Novel	VGF	VGF nerve growth factor inducible	Regulation of Insulin-like Growth Factor (IGF) transport and uptake by Insulin-like Growth Factor Binding Proteins (IGFBPs) Post-translational protein phosphorylation NGF-stimulated transcription
Novel	ZNF3	zinc finger protein 3	Generic Transcription Pathway
Novel	ZNHIT1	zinc finger HIT-type containing 1
	FXN	frataxin	Mitochondrial protein import Mitochondrial protein import Mitochondrial iron-sulfur cluster biogenesis	Iron Ferrous gluconate Ferrous succinate Ferrous ascorbate Ferrous fumarate Ferrous glycine sulfate	Friedreich ataxia
	MARK3	microtubule affinity regulating kinase 3	RAF activation MAP2K and MAPK activation Negative regulation of MAPK pathway Signaling by moderate kinase activity BRAF mutants Signaling by high-kinase activity BRAF mutants Signaling by BRAF and RAF fusions Paradoxical activation of RAF signaling by kinase inactive BRAF Signaling downstream of RAS mutants Signaling by RAF1 mutants	Fostamatinib
	NPSR1	neuropeptide S receptor 1	Peptide ligand-binding receptors G alpha (q) signalling events G alpha (s) signalling events ADORA2B mediated anti-inflammatory cytokines production	Halothane
	PMPCA	peptidase, mitochondrial processing subunit alpha	Mitochondrial protein import Processing of SMDT1
	PTGER4	prostaglandin E receptor 4	Prostanoid ligand receptors G alpha (s) signalling events ADORA2B mediated anti-inflammatory cytokines production	Dinoprostone Misoprostol Limaprost Castor oil Grapiprant

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