NUTF2 - New-wiki

Novel	Interactant Symbol	Name	Associated Pathways Hide	Binding Drugs Hide
Novel	CANX	calnexin	Assembly of Viral Components at the Budding Site MHC class II antigen presentation Interleukin-35 Signalling Calnexin/calreticulin cycle Interleukin-27 signaling Maturation of spike protein Maturation of spike protein Antigen Presentation: Folding, assembly and peptide loading of class I MHC Antigen Presentation: Folding, assembly and peptide loading of class I MHC	Antihemophilic factor, human recombinant Tenecteplase Lanoteplase Calcium citrate Calcium Phosphate Lonoctocog alfa Moroctocog alfa Calcium phosphate dihydrate
Novel	GLRX2	glutaredoxin 2		Glutathione
Novel	NFAT5	nuclear factor of activated T cells 5
Novel	SF3B3	splicing factor 3b subunit 3	mRNA Splicing - Major Pathway mRNA Splicing - Minor Pathway	Quercetin
Novel	TERF2	telomeric repeat binding factor 2	Recognition and association of DNA glycosylase with site containing an affected pyrimidine Cleavage of the damaged pyrimidine Recognition and association of DNA glycosylase with site containing an affected purine Recognition and association of DNA glycosylase with site containing an affected purine Cleavage of the damaged purine Cleavage of the damaged purine Meiotic synapsis Packaging Of Telomere Ends Telomere Extension By Telomerase Polymerase switching on the C-strand of the telomere Processive synthesis on the C-strand of the telomere Telomere C-strand (Lagging Strand) Synthesis Telomere C-strand synthesis initiation Removal of the Flap Intermediate from the C-strand DNA Damage/Telomere Stress Induced Senescence Inhibition of DNA recombination at telomere
Novel	WWP2	WW domain containing E3 ubiquitin protein ligase 2	Regulation of PTEN stability and activity NOTCH3 Activation and Transmission of Signal to the Nucleus
	BEND7	BEN domain containing 7
	BRWD1	bromodomain and WD repeat domain containing 1	Interleukin-7 signaling Interleukin-7 signaling Chromatin modifying enzymes
	CAMK2G	calcium/calmodulin dependent protein kinase II gamma	CaMK IV-mediated phosphorylation of CREB HSF1-dependent transactivation Trafficking of AMPA receptors Unblocking of NMDA receptors, glutamate binding and activation Unblocking of NMDA receptors, glutamate binding and activation CREB1 phosphorylation through the activation of CaMKII/CaMKK/CaMKIV cascasde Ras activation upon Ca2+ influx through NMDA receptor Phase 0 - rapid depolarisation Ion homeostasis RAF activation RAF/MAP kinase cascade Signaling by moderate kinase activity BRAF mutants Signaling by BRAF and RAF fusions Paradoxical activation of RAF signaling by kinase inactive BRAF Interferon gamma signaling Regulation of MECP2 expression and activity Ion transport by P-type ATPases Assembly and cell surface presentation of NMDA receptors Negative regulation of NMDA receptor-mediated neuronal transmission Long-term potentiation Signaling downstream of RAS mutants Signaling by RAF1 mutants	Bosutinib 1-tert-butyl-3-(3-methylbenzyl)-1H-pyrazolo[3,4-d]pyrimidin-4-amine Fostamatinib
	CCDC106	coiled-coil domain containing 106
	CCDC150	coiled-coil domain containing 150
	CCDC158	coiled-coil domain containing 158
	CHCHD3	coiled-coil-helix-coiled-coil-helix domain containing 3	Mitochondrial protein import Cristae formation
	CHMP4A	charged multivesicular body protein 4A	Budding and maturation of HIV virion Macroautophagy Endosomal Sorting Complex Required For Transport (ESCRT) HCMV Late Events Late endosomal microautophagy Sealing of the nuclear envelope (NE) by ESCRT-III Translation of Replicase and Assembly of the Replication Transcription Complex Translation of Replicase and Assembly of the Replication Transcription Complex
	CKMT1A	creatine kinase, mitochondrial 1A	Creatine metabolism	Creatine Phosphocreatine
	CKMT1B	creatine kinase, mitochondrial 1B	Creatine metabolism	Creatine Phosphocreatine
	CLPP	caseinolytic mitochondrial matrix peptidase proteolytic subunit		N-Formylmethionine
	FAM50B	family with sequence similarity 50 member B
	HMG20A	high mobility group 20A
	HMG20B	high mobility group 20B	HDACs deacetylate histones Potential therapeutics for SARS Factors involved in megakaryocyte development and platelet production

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