Search Results for: MAD1L1

78 interactions involving MAD1L1 - mitotic arrest deficient 1 like 1 found:

Sort by: Symbol Number of Pathways Number of Drugs Number of Diseases
Novel Interactant Symbol Name
Associated Pathways
Binding Drugs
Associated Diseases
Novel AIMP2 aminoacyl tRNA synthetase complex interacting multifunctional protein 2
  • Selenoamino acid metabolism
  • Cytosolic tRNA aminoacylation
Novel ANXA5 annexin A5
  • Platelet degranulation
  • Fluocinolone acetonide
  • L-Alpha-Glycerophosphorylserine
  • L-thioproline
  • K201 free base
  • sn-glycero-3-phosphoethanolamine
  • 1,4-Dideoxy-O2-Sulfo-Glucuronic Acid
  • N,O6-Disulfo-Glucosamine
  • 1,4-Dideoxy-5-Dehydro-O2-Sulfo-Glucuronic Acid
  • Copper
Novel CCND2 cyclin D2
  • Cyclin D associated events in G1
  • Regulation of RUNX1 Expression and Activity
  • Defective binding of RB1 mutants to E2F1,(E2F2, E2F3)
  • Testicular cancer
Novel CHERP calcium homeostasis endoplasmic reticulum protein
  • mRNA Splicing - Major Pathway
Novel CHST12 carbohydrate sulfotransferase 12
  • Chondroitin sulfate biosynthesis
Novel FSCN1 fascin actin-bundling protein 1
  • Interleukin-4 and Interleukin-13 signaling
Novel HOXA10 homeobox A10
  • Calcitriol
Novel NXPH1 neurexophilin 1
Novel PIN4 peptidylprolyl cis/trans isomerase, NIMA-interacting 4
Novel PRKAR1B protein kinase cAMP-dependent type I regulatory subunit beta
  • PKA activation
  • PKA activation in glucagon signalling
  • DARPP-32 events
  • Glucagon-like Peptide-1 (GLP1) regulates insulin secretion
  • Vasopressin regulates renal water homeostasis via Aquaporins
  • CREB1 phosphorylation through the activation of Adenylate Cyclase
  • Hedgehog 'off' state
  • ADORA2B mediated anti-inflammatory cytokines production
  • FCGR3A-mediated IL10 synthesis
  • Factors involved in megakaryocyte development and platelet production
Novel RPA3 replication protein A3
  • Translesion synthesis by REV1
  • Recognition of DNA damage by PCNA-containing replication complex
  • Translesion Synthesis by POLH
  • Removal of the Flap Intermediate from the C-strand
  • Activation of ATR in response to replication stress
  • Regulation of HSF1-mediated heat shock response
  • HSF1 activation
  • Mismatch repair (MMR) directed by MSH2:MSH6 (MutSalpha)
  • Mismatch repair (MMR) directed by MSH2:MSH3 (MutSbeta)
  • Mismatch repair (MMR) directed by MSH2:MSH3 (MutSbeta)
  • PCNA-Dependent Long Patch Base Excision Repair
  • Translesion synthesis by POLK
  • Translesion synthesis by POLI
  • Termination of translesion DNA synthesis
  • HDR through Single Strand Annealing (SSA)
  • HDR through Homologous Recombination (HRR)
  • Processing of DNA double-strand break ends
  • Presynaptic phase of homologous DNA pairing and strand exchange
  • Formation of Incision Complex in GG-NER
  • Gap-filling DNA repair synthesis and ligation in GG-NER
  • Dual Incision in GG-NER
  • Dual incision in TC-NER
  • Gap-filling DNA repair synthesis and ligation in TC-NER
  • Fanconi Anemia Pathway
  • Regulation of TP53 Activity through Phosphorylation
  • Activation of the pre-replicative complex
  • Removal of the Flap Intermediate
  • G2/M DNA damage checkpoint
  • Meiotic recombination
Novel S100P S100 calcium binding protein P
  • Neutrophil degranulation
  • Cromoglicic acid
Novel STAM signal transducing adaptor molecule
  • EGFR downregulation
  • Metalloprotease DUBs
  • Negative regulation of MET activity
  • Cargo recognition for clathrin-mediated endocytosis
  • Clathrin-mediated endocytosis
  • InlB-mediated entry of Listeria monocytogenes into host cell
  • Endosomal Sorting Complex Required For Transport (ESCRT)
Novel TTYH3 tweety family member 3
  • Stimuli-sensing channels
Novel TULP4 TUB like protein 4
  • Neddylation
ALOX5 arachidonate 5-lipoxygenase
  • Synthesis of 5-eicosatetraenoic acids
  • Synthesis of Leukotrienes (LT) and Eoxins (EX)
  • Synthesis of Lipoxins (LX)
  • Interleukin-4 and Interleukin-13 signaling
  • Neutrophil degranulation
  • Interleukin-18 signaling
  • Biosynthesis of D-series resolvins
  • Biosynthesis of maresins
  • Biosynthesis of E-series 18(S)-resolvins
  • Biosynthesis of aspirin-triggered D-series resolvins
  • Biosynthesis of E-series 18(R)-resolvins
  • Biosynthesis of DPAn-3-derived protectins and resolvins
  • Biosynthesis of DPAn-3-derived maresins
  • Biosynthesis of DPAn-3-derived 13-series resolvins
  • Biosynthesis of electrophilic ω-3 PUFA oxo-derivatives
  • Vitamin E
  • Masoprocol
  • Aminosalicylic acid
  • Mesalazine
  • Montelukast
  • Diethylcarbamazine
  • Zileuton
  • Sulfasalazine
  • Meclofenamic acid
  • Balsalazide
  • Minocycline
  • Hyperforin
  • Resveratrol
  • Licofelone
  • MLN-977
  • Morniflumate
  • Diacerein
  • Fostamatinib
  • Rhein
  • alpha-Tocopherol succinate
  • D-alpha-Tocopherol acetate
AMOTL2 angiomotin like 2
  • Signaling by Hippo
ATG5 autophagy related 5
  • Macroautophagy
  • Macroautophagy
  • PINK1-PRKN Mediated Mitophagy
  • Receptor Mediated Mitophagy
  • Negative regulators of DDX58/IFIH1 signaling
BAG5 BAG cochaperone 5
  • Regulation of HSF1-mediated heat shock response
BIRC2 baculoviral IAP repeat containing 2
  • Apoptotic cleavage of cellular proteins
  • NOD1/2 Signaling Pathway
  • TICAM1, RIP1-mediated IKK complex recruitment
  • RIPK1-mediated regulated necrosis
  • Regulation of TNFR1 signaling
  • TNFR1-induced NFkappaB signaling pathway
  • TNFR2 non-canonical NF-kB pathway
  • Regulation of necroptotic cell death
  • TNF receptor superfamily (TNFSF) members mediating non-canonical NF-kB pathway
  • Ub-specific processing proteases
  • IKK complex recruitment mediated by RIP1

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