Search Results for: GPX1

15 interactions involving GPX1 - glutathione peroxidase 1 found:

Sort by: Symbol Number of Pathways Number of Drugs Number of Diseases
Novel Interactant Symbol Name
Associated Pathways
Binding Drugs
Associated Diseases
Novel ACKR2 atypical chemokine receptor 2
  • Chemokine receptors bind chemokines
Novel CAMP cathelicidin antimicrobial peptide
  • Neutrophil degranulation
  • Antimicrobial peptides
  • Selenocysteine
Novel CISH cytokine inducible SH2 containing protein
  • Interleukin-7 signaling
  • Neddylation
  • Growth hormone receptor signaling
Novel EBNA1BP2 EBNA1 binding protein 2
  • Major pathway of rRNA processing in the nucleolus and cytosol
Novel IDH2 isocitrate dehydrogenase (NADP(+)) 2
  • Transcriptional activation of mitochondrial biogenesis
  • Citric acid cycle (TCA cycle)
  • Isocitric Acid
  • Enasidenib
Novel ITGA9 integrin subunit alpha 9
  • Integrin cell surface interactions
  • Integrin cell surface interactions
  • ECM proteoglycans
  • Signal transduction by L1
  • Congenital muscular dystrophies (CMD/MDC), including: Merosin-deficient CMD (MDC1A); Ullrich CMD (UCMD); Integrin alpha7-deficient CMD; CMD with joint hyperlaxity (CMDH); CMD with epidermolysis bullosa; Walker-Warburg syndrome (WWS); Muscle-eye-brain disease (MEB); Fukuyama CMD (FCMD); CMD with muscle hypertrophy (MDC1C); CMD with severe intellectual impairment and abnormal glycosylation (MDC1D); Rigid spine syndrome (RSS); LMNA-deficient CMD; CMD with respiratory failure and muscle hypertrophy (MDC1B); Bethlem myopathy
Novel MLH1 mutL homolog 1
  • Mismatch repair (MMR) directed by MSH2:MSH6 (MutSalpha)
  • Mismatch repair (MMR) directed by MSH2:MSH3 (MutSbeta)
  • Defective Mismatch Repair Associated With MLH1
  • Defective Mismatch Repair Associated With PMS2
  • TP53 Regulates Transcription of DNA Repair Genes
  • Meiotic recombination
  • Colorectal cancer
  • Mismatch repair deficiency, including: Hereditary non-polyposis colorectal cancer (HNPCC); Lynch syndrome; Muir-Torre syndrome; Turcot syndrome
  • Endometrial Cancer
  • Ovarian cancer
Novel MST1R macrophage stimulating 1 receptor
  • Signaling by MST1
  • Fostamatinib
Novel RHOA ras homolog family member A
  • GPVI-mediated activation cascade
  • Axonal growth inhibition (RHOA activation)
  • Rho GTPase cycle
  • PI3K/AKT activation
  • Axonal growth stimulation
  • TGF-beta receptor signaling in EMT (epithelial to mesenchymal transition)
  • TGF-beta receptor signaling in EMT (epithelial to mesenchymal transition)
  • G beta:gamma signalling through PI3Kgamma
  • EPHB-mediated forward signaling
  • EPHB-mediated forward signaling
  • EPHA-mediated growth cone collapse
  • EPHA-mediated growth cone collapse
  • PCP/CE pathway
  • G alpha (12/13) signalling events
  • Sema4D mediated inhibition of cell attachment and migration
  • Sema4D induced cell migration and growth-cone collapse
  • Sema4D induced cell migration and growth-cone collapse
  • VEGFA-VEGFR2 Pathway
  • RHO GTPases activate PKNs
  • RHO GTPases activate CIT
  • RHO GTPases activate CIT
  • RHO GTPases activate KTN1
  • RHO GTPases Activate ROCKs
  • RHO GTPases Activate ROCKs
  • RHO GTPases Activate Formins
  • RHO GTPases Activate Rhotekin and Rhophilins
  • RHO GTPases Activate Rhotekin and Rhophilins
  • Ovarian tumor domain proteases
  • ERBB2 Regulates Cell Motility
  • Neutrophil degranulation
  • PTK6 Regulates RHO GTPases, RAS GTPase and MAP kinases
  • SLIT2:ROBO1 increases RHOA activity
  • Guanosine-5'-Diphosphate
Novel UQCRC1 ubiquinol-cytochrome c reductase core protein 1
  • Respiratory electron transport
  • 2-Hexyloxy-6-Hydroxymethyl-Tetrahydro-Pyran-3,4,5-Triol
  • Myxothiazol
  • 6-Hydroxy-5-undecyl-4,7-benzothiazoledione
  • Azoxystrobin
  • (5S)-3-ANILINO-5-(2,4-DIFLUOROPHENYL)-5-METHYL-1,3-OXAZOLIDINE-2,4-DIONE
  • (S)-famoxadone
  • METHYL (2Z)-3-METHOXY-2-{2-[(E)-2-PHENYLVINYL]PHENYL}ACRYLATE
  • 2-Nonyl-4-quinolinol 1-oxide
  • Ubiquinone Q2
ABL1 ABL proto-oncogene 1, non-receptor tyrosine kinase
  • Regulation of actin dynamics for phagocytic cup formation
  • Role of ABL in ROBO-SLIT signaling
  • Role of ABL in ROBO-SLIT signaling
  • Myogenesis
  • Myogenesis
  • RHO GTPases Activate WASPs and WAVEs
  • HDR through Single Strand Annealing (SSA)
  • Recruitment and ATM-mediated phosphorylation of repair and signaling proteins at DNA double strand breaks
  • Cyclin D associated events in G1
  • RUNX1 regulates transcription of genes involved in differentiation of HSCs
  • RUNX2 regulates osteoblast differentiation
  • FCGR3A-mediated phagocytosis
  • Factors involved in megakaryocyte development and platelet production
  • ATP
  • Imatinib
  • Dasatinib
  • N-[4-Methyl-3-[[4-(3-Pyridinyl)-2-Pyrimidinyl]Amino]Phenyl]-3-Pyridinecarboxamide
  • Nilotinib
  • XL228
  • Bosutinib
  • 2-{[(6-OXO-1,6-DIHYDROPYRIDIN-3-YL)METHYL]AMINO}-N-[4-PROPYL-3-(TRIFLUOROMETHYL)PHENYL]BENZAMIDE
  • 1-[4-(PYRIDIN-4-YLOXY)PHENYL]-3-[3-(TRIFLUOROMETHYL)PHENYL]UREA
  • Myristic acid
  • PD-166326
  • 5-[3-(2-METHOXYPHENYL)-1H-PYRROLO[2,3-B]PYRIDIN-5-YL]-N,N-DIMETHYLPYRIDINE-3-CARBOXAMIDE
  • 2-amino-5-[3-(1-ethyl-1H-pyrazol-5-yl)-1H-pyrrolo[2,3-b]pyridin-5-yl]-N,N-dimethylbenzamide
  • Regorafenib
  • Ponatinib
  • Fostamatinib
  • Brigatinib
  • Radotinib
  • Chronic myeloid leukemia (CML)
  • Acute lymphoblastic leukemia (ALL) (precursor B lymphoblastic leukemia)
ABL2 ABL proto-oncogene 2, non-receptor tyrosine kinase
  • Role of ABL in ROBO-SLIT signaling
  • Role of ABL in ROBO-SLIT signaling
  • Negative regulation of FLT3
  • ATP
  • Dasatinib
  • XL228
  • K-00546
  • Fostamatinib
FAM9B family with sequence similarity 9 member B
MAPK6 mitogen-activated protein kinase 6
  • MAPK6/MAPK4 signaling
  • Acetylsalicylic acid
  • Minocycline
SELENBP1 selenium binding protein 1

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