Search Results for: EXOSC5

84 interactions involving EXOSC5 - exosome component 5 found:

Sort by: Symbol Number of Pathways Number of Drugs Number of Diseases
Novel Interactant Symbol Name
Associated Pathways
Binding Drugs
Associated Diseases
Novel HAMP hepcidin antimicrobial peptide
  • Hemochromatosis (HFE); Juvenile hemochromatosis (JH)
Novel KMT2A lysine methyltransferase 2A
  • PKMTs methylate histone lysines
  • RUNX1 regulates genes involved in megakaryocyte differentiation and platelet function
  • RUNX1 regulates transcription of genes involved in differentiation of HSCs
  • RUNX1 regulates transcription of genes involved in differentiation of HSCs
  • Transcriptional regulation of granulopoiesis
  • Acute lymphoblastic leukemia (ALL) (precursor T lymphoblastic leukemia)
  • Acute lymphoblastic leukemia (ALL) (precursor B lymphoblastic leukemia)
Novel PAF1 PAF1 homolog, Paf1/RNA polymerase II complex component
  • Formation of RNA Pol II elongation complex
  • RNA Polymerase II Pre-transcription Events
  • RNA Polymerase II Transcription Elongation
  • E3 ubiquitin ligases ubiquitinate target proteins
Novel PRODH2 proline dehydrogenase 2
  • Glyoxylate metabolism and glycine degradation
  • Proline catabolism
ACOT11 acyl-CoA thioesterase 11
  • Mitochondrial Fatty Acid Beta-Oxidation
ADAMTSL4 ADAMTS like 4
  • Defective B3GALTL causes Peters-plus syndrome (PpS)
  • O-glycosylation of TSR domain-containing proteins
  • Ectopia lentis
BIRC2 baculoviral IAP repeat containing 2
  • Apoptotic cleavage of cellular proteins
  • NOD1/2 Signaling Pathway
  • TICAM1, RIP1-mediated IKK complex recruitment
  • RIPK1-mediated regulated necrosis
  • Regulation of TNFR1 signaling
  • TNFR1-induced NFkappaB signaling pathway
  • TNFR2 non-canonical NF-kB pathway
  • Regulation of necroptotic cell death
  • TNF receptor superfamily (TNFSF) members mediating non-canonical NF-kB pathway
  • Ub-specific processing proteases
  • IKK complex recruitment mediated by RIP1
BORCS6 BLOC-1 related complex subunit 6
CALCOCO2 calcium binding and coiled-coil domain 2
CCDC88B coiled-coil domain containing 88B
CDK5RAP1 CDK5 regulatory subunit associated protein 1
DAAM2 dishevelled associated activator of morphogenesis 2
DDIT4L DNA damage inducible transcript 4 like
DHRS2 dehydrogenase/reductase 2
DIS3 DIS3 homolog, exosome endoribonuclease and 3'-5' exoribonuclease
  • ATF4 activates genes in response to endoplasmic reticulum stress
  • mRNA decay by 3' to 5' exoribonuclease
  • Butyrate Response Factor 1 (BRF1) binds and destabilizes mRNA
  • Tristetraprolin (TTP, ZFP36) binds and destabilizes mRNA
  • KSRP (KHSRP) binds and destabilizes mRNA
  • Major pathway of rRNA processing in the nucleolus and cytosol
DMRTB1 DMRT like family B with proline rich C-terminal 1
DOCK8 dedicator of cytokinesis 8
  • Factors involved in megakaryocyte development and platelet production
  • Non-syndromic autosomal dominant mental retardation
EFHC2 EF-hand domain containing 2
EXOSC1 exosome component 1
  • ATF4 activates genes in response to endoplasmic reticulum stress
  • mRNA decay by 3' to 5' exoribonuclease
  • Butyrate Response Factor 1 (BRF1) binds and destabilizes mRNA
  • Tristetraprolin (TTP, ZFP36) binds and destabilizes mRNA
  • KSRP (KHSRP) binds and destabilizes mRNA
  • Major pathway of rRNA processing in the nucleolus and cytosol
EXOSC10 exosome component 10
  • Major pathway of rRNA processing in the nucleolus and cytosol

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