NR1D2 and NBPF19

Data Source:
BioGRID (two hybrid)

		NR1D2	NBPF19
Description		nuclear receptor subfamily 1 group D member 2	NBPF member 19
Image			No pdb structure
GO Annotations	Cellular Component	Chromatin Nucleus Nucleoplasm Cytoplasm	Cytoplasm
	Molecular Function	RNA Polymerase II Cis-regulatory Region Sequence-specific DNA Binding DNA-binding Transcription Factor Activity, RNA Polymerase II-specific DNA-binding Transcription Repressor Activity, RNA Polymerase II-specific Nuclear Receptor Activity Protein Binding Zinc Ion Binding Sequence-specific Double-stranded DNA Binding
	Biological Process	Negative Regulation Of Transcription By RNA Polymerase II Regulation Of Transcription, DNA-templated Transcription Initiation From RNA Polymerase II Promoter Hormone-mediated Signaling Pathway Regulation Of Lipid Metabolic Process Cell Differentiation Intracellular Receptor Signaling Pathway Regulation Of Circadian Rhythm Negative Regulation Of Transcription, DNA-templated Positive Regulation Of Transcription, DNA-templated Positive Regulation Of Transcription By RNA Polymerase II Circadian Behavior Regulation Of Inflammatory Response Negative Regulation Of Inflammatory Response Lipid Homeostasis Energy Homeostasis Regulation Of Skeletal Muscle Cell Differentiation
Pathways		Nuclear Receptor transcription pathway
Drugs		SR-9009 SR-9011
Diseases
GWAS		Acne (severe) ( 24927181) Angiotensin-converting enzyme inhibitor intolerance ( 28030426) Asthma ( 29273806) Cognitive ability ( 29186694) Extremely high intelligence ( 29520040) General cognitive ability ( 29844566) Intelligence ( 28530673) Intelligence (MTAG) ( 29326435) Metabolite levels ( 23823483) Parkinson's disease progression (cognitive) ( 33111402) Refractive error ( 32231278)	Serum uric acid levels ( 30993211)
Interacting Genes		53 interacting genes: CRY1 CSNK1E CSNK2A2 CUL1 CYSRT1 DELEC1 EFEMP2 GTF2B HDAC1 HOXA1 KRT40 KRTAP1-1 KRTAP1-3 KRTAP10-1 KRTAP10-8 KRTAP10-9 KRTAP12-2 KRTAP12-3 KRTAP3-2 KRTAP3-3 KRTAP4-2 KRTAP5-6 KRTAP6-2 KRTAP9-2 KRTAP9-3 KRTAP9-8 LGALS8 MEOX2 MID2 MYLIP MYO15B NBPF19 NCOA5 NCOR1 NOTCH2NLA NR1D1 PCSK5 PRMT6 PROP1 RBPMS RGN RORC SIN3B TAF6 TAF9 TBC1D21 TENT5B TRIM27 TRIM55 TRIM63 TRIP6 UBE2I ZNF587	223 interacting genes: ADAM12 ADAMTSL4 AGXT ALDH16A1 ALPP ANKS1A AQP1 ATG9A ATP5F1D BCAM BMP7 BRME1 CARHSP1 CATSPER1 CCER1 CD164 CELF5 CERK CHCHD3 CHIC2 CHRD CHRNG CNNM3 COL8A1 CREB5 CRH CRY2 CST2 CST9L CTNNBIP1 CTSZ CXCL16 CYHR1 CYP21A2 CYSRT1 DAGLB DALRD3 DBH DGKQ DHRS1 DMRT3 DOCK2 DRD5 EMC7 F10 FADS2 FAM221A FAM71C FAM90A1 FBXW5 FRS3 FTHL17 FZD10 GLP1R GLYAT GNE GSTP1 HAPLN2 HBA1 HBA2 HBZ HCK HHEX HOXA1 HOXB9 HOXC8 HPCAL1 HSPA12B ICAM4 IL10 INO80B INS ITGB2 ITGB4 ITGB5 JOSD1 KCNS2 KCTD15 KLHL38 KLK8 KPRP KRT83 KRTAP10-1 KRTAP10-10 KRTAP10-5 KRTAP10-8 KRTAP10-9 KRTAP12-1 KRTAP12-2 KRTAP12-3 KRTAP12-4 KRTAP13-2 KRTAP13-3 KRTAP13-4 KRTAP2-3 KRTAP2-4 KRTAP26-1 KRTAP4-11 KRTAP4-2 KRTAP4-4 KRTAP4-5 KRTAP5-11 KRTAP5-3 KRTAP5-4 KRTAP5-6 KRTAP5-9 KRTAP9-2 KRTAP9-3 KRTAP9-8 LCE1A LCE1B LCE1D LCE1E LCE1F LCE2B LCE2C LCE2D LCE3A LCE3C LCE3D LCE3E LCE4A LCE5A LMNTD2 LNX1 LRFN4 LYVE1 MACO1 MAPKBP1 MELTF MFSD13A MOS MRGBP MRPL40 MTA1 MXD3 MXI1 MYO15B MYPOP NECTIN2 NECTIN3 NEDD9 NMU NPDC1 NR1D2 NTM NTN4 OLFM2 OTX1 P2RX4 P2RX7 P2RY6 PCSK5 PGAP6 PHLDA1 PIGS PLEKHN1 PRF1 PRR35 PSMA1 PTK7 PTPMT1 PVR R3HDM2 RAB3IL1 RAMP3 RASD1 RECK RNF111 RPS19BP1 RTN4RL1 SCNM1 SEMA3B SEMA4C SHFL SLC22A5 SLC23A1 SLC43A2 SLC5A5 SLC6A20 SMCP SPATA24 SPATA8 SPG7 SPPL2C SPRY1 STAC STK16 TAPBPL TCAF1 THAP7 TLE5 TMEFF2 TMEM150A TMIE TNIP3 TNS2 TRAPPC14 TRIM42 TROAP TSPAN4 TTPA UTP23 UXT VASN WDR25 ZDHHC1 ZNF124 ZNF319 ZNF330 ZNF408 ZNF414 ZNF417 ZNF440 ZNF446 ZNF497 ZNF580 ZNF581 ZNF587 ZNF648 ZNF672 ZNF786 ZNF837
Entrez ID		9975	101060226
HPRD ID		03809
Ensembl ID		ENSG00000174738	ENSG00000271383
Uniprot IDs		B4DXD3 F1D8P2 Q14995
PDB IDs		2V0V 2V7C 3CQV 4N73
Enriched GO Terms of Interacting Partners?
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