TRANK1 and DCLK3

Data Source:
BioGRID (biochemical)

		TRANK1	DCLK3
Description		tetratricopeptide repeat and ankyrin repeat containing 1	doublecortin like kinase 3
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component		Nucleus Cytoplasm
	Molecular Function		Protein Kinase Activity ATP Binding Protein Serine Kinase Activity Protein Threonine Kinase Activity
	Biological Process		Peptidyl-serine Phosphorylation
Pathways
Drugs			Fostamatinib
Diseases
GWAS		anorexia nervosa, attention-deficit/hyperactivity disorder, autism spectrum disorder, bipolar disorder, major depression, obsessive-compulsive disorder, schizophrenia, or Tourette syndrome (pleiotropy) ( 31835028) Apolipoprotein A1 levels ( 32203549) Autism spectrum disorder or schizophrenia ( 28540026) Bipolar disorder ( 22182935 28115744 24618891 31043756 28072414 27329760) Bipolar disorder with mood-incongruent psychosis ( 23092984) Bipolar I disorder ( 31043756) Chronotype ( 30696823) Electrocardiogram morphology (amplitude at temporal datapoints) ( 32916098) HDL cholesterol ( 30275531) HDL cholesterol levels ( 32203549) Iris color (L* coordinate) ( 29109912) Mean platelet volume ( 32888494) Morning person ( 30696823) Platelet distribution width ( 27863252) Pulse pressure ( 30224653) Schizophrenia ( 28991256 25056061 29483656 30285260) Schizophrenia or bipolar disorder ( 24280982) Subjective response to lithium treatment ( 26503763) Triglycerides ( 30275531)	anorexia nervosa, attention-deficit/hyperactivity disorder, autism spectrum disorder, bipolar disorder, major depression, obsessive-compulsive disorder, schizophrenia, or Tourette syndrome (pleiotropy) ( 31835028) Chronotype ( 30696823) Morning person ( 30696823) Schizophrenia ( 28991256) Takayasu arteritis ( 25604533) White matter hyperintensity volume ( 32062564)
Interacting Genes
Entrez ID		9881	85443
HPRD ID		19247	19338
Ensembl ID		ENSG00000168016	ENSG00000163673
Uniprot IDs		A0A2R8YEM9 O15050	B3KVM3 Q9C098
PDB IDs
Enriched GO Terms of Interacting Partners?
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