DDX46 and JADE2

Data Source:
BioGRID (proximity labelling technology)

		DDX46	JADE2
Description		DEAD-box helicase 46	jade family PHD finger 2
Image			No pdb structure
GO Annotations	Cellular Component	Fibrillar Center Nucleus Nucleoplasm Cajal Body Membrane Nuclear Speck	Histone Acetyltransferase Complex Nucleoplasm Extracellular Exosome
	Molecular Function	RNA Binding RNA Helicase Activity ATP Binding	Protein Binding Transferase Activity Metal Ion Binding
	Biological Process	MRNA Splicing, Via Spliceosome	Protein Ubiquitination Histone H3 Acetylation Histone H4-K5 Acetylation Histone H4-K8 Acetylation Histone H4-K12 Acetylation Histone H4-K16 Acetylation
Pathways		mRNA Splicing - Major Pathway	HATs acetylate histones
Drugs
Diseases
GWAS		Height ( 18391951)	Adult body size ( 32376654) Age at first birth ( 27798627) Body mass index ( 28892062) Brain morphology (MOSTest) ( 32665545) Coffee consumption ( 31046077) Electrocardiogram morphology (amplitude at temporal datapoints) ( 32916098) Hand grip strength ( 29691431) Household income (MTAG) ( 31844048) Mental health study participation (completed survey) ( 31263887) Monocyte percentage of white cells ( 32888494) Multiple sclerosis ( 31604244) Neutrophil count ( 32888494) Platelet distribution width ( 27863252) Subcortical volume (MOSTest) ( 32665545) Type 2 diabetes ( 28869590) White blood cell count ( 32888494)
Interacting Genes		3 interacting genes: APBB1 LINC01554 SRPK2	16 interacting genes: CBX8 CDCA7L CSNK2A1 FBXO7 GAS2L2 GORASP2 H3-4 ING4 ING5 MEAF6 PACSIN1 SASH1 ZBTB3 ZBTB5 ZNF417 ZNF496
Entrez ID		9879	23338
HPRD ID		10862	15124
Ensembl ID		ENSG00000145833	ENSG00000043143
Uniprot IDs		A0A0C4DG89 Q7L014	A0A0C4DFT8 B3KPL2 B4DFY8 G3XAA4 Q9NQC1
PDB IDs		6Y50 6Y53 6Y5Q
Enriched GO Terms of Interacting Partners?
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