NRG2 and HNRNPLL

Data Source:
BioGRID (affinity chromatography technology)

		NRG2	HNRNPLL
Description		neuregulin 2	heterogeneous nuclear ribonucleoprotein L like
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Extracellular Region Extracellular Space Plasma Membrane Integral Component Of Membrane	Nucleus Membrane
	Molecular Function	Signaling Receptor Binding Growth Factor Activity	RNA Binding MRNA Binding Protein Binding
	Biological Process	MAPK Cascade Signal Transduction Nervous System Development Intracellular Signal Transduction ERBB2 Signaling Pathway Animal Organ Development Positive Regulation Of Protein Kinase B Signaling Regulation Of Cell Motility	MRNA Processing Positive Regulation Of RNA Splicing Regulation Of RNA Splicing
Pathways		Signaling by ERBB2 Signaling by ERBB4 Signaling by ERBB4 SHC1 events in ERBB2 signaling SHC1 events in ERBB2 signaling PI3K events in ERBB4 signaling SHC1 events in ERBB4 signaling Nuclear signaling by ERBB4 PIP3 activates AKT signaling GRB7 events in ERBB2 signaling Downregulation of ERBB2:ERBB3 signaling GRB2 events in ERBB2 signaling PI3K events in ERBB2 signaling Constitutive Signaling by Aberrant PI3K in Cancer RAF/MAP kinase cascade ERBB2 Regulates Cell Motility PI5P, PP2A and IER3 Regulate PI3K/AKT Signaling ERBB2 Activates PTK6 Signaling Downregulation of ERBB2 signaling Signaling by ERBB2 KD Mutants Signaling by ERBB2 TMD/JMD mutants
Drugs
Diseases
GWAS		Body mass index ( 26426971) Disturbances of the gamma-frequency band of electroencephalography measures in schizophrenia ( 28922980) Gut microbiota (bacterial taxa, hurdle binary method) ( 32572223)	Body mass index ( 28892062)
Interacting Genes		2 interacting genes: ERBB3 ERBB4	42 interacting genes: ADAMTSL4 ATXN1 BANP BARD1 BHLHE40 BOLL CALCOCO2 DAB1 DDX39A DDX39B EFHC2 FAM9B GOPC HNRNPK IKZF3 KHDRBS2 KRT31 KRT40 KRTAP10-3 MAGED1 MDFI MID2 PAXIP1 PCBP1 PNMA1 RBM10 RBPMS REL RHOXF2 SKIL SPRY2 SRSF11 SSX2IP SUMO2 TADA2A THAP1 TLE5 TMCC2 TRIM23 TRIM27 UBE2I VAC14
Entrez ID		9542	92906
HPRD ID		04821	13667
Ensembl ID		ENSG00000158458	ENSG00000143889
Uniprot IDs		F5GZS7 O14511	A0A0S2Z6K1 A8K894 Q8WVV9
PDB IDs
Enriched GO Terms of Interacting Partners?
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