BAG5 and IGHG4

Data Source:
BioGRID (affinity chromatography technology)

		BAG5	IGHG4
Description		BAG cochaperone 5	immunoglobulin heavy constant gamma 4 (G4m marker)
Image			No pdb structure
GO Annotations	Cellular Component	Nucleus Cytoplasm Mitochondrion Cytosol Membrane Inclusion Body Perinuclear Region Of Cytoplasm	Extracellular Region Extracellular Space External Side Of Plasma Membrane Immunoglobulin Complex, Circulating Extracellular Exosome Blood Microparticle
	Molecular Function	Adenyl-nucleotide Exchange Factor Activity Protein Binding Protein Kinase Binding Heat Shock Protein Binding Ubiquitin Protein Ligase Binding Chaperone Binding	Antigen Binding Immunoglobulin Receptor Binding
	Biological Process	Protein Folding Golgi Organization Negative Regulation Of Neuron Projection Development Negative Regulation Of Protein Ubiquitination Negative Regulation Of Proteasomal Ubiquitin-dependent Protein Catabolic Process Protein Stabilization Regulation Of Ubiquitin-protein Transferase Activity Negative Regulation Of Ubiquitin-protein Transferase Activity Negative Regulation Of Protein Refolding Neuron Death Regulation Of Inclusion Body Assembly Regulation Of Cellular Response To Heat Negative Regulation Of Oxidative Stress-induced Intrinsic Apoptotic Signaling Pathway	Phagocytosis, Recognition Phagocytosis, Engulfment Complement Activation Complement Activation, Classical Pathway Cytokine-mediated Signaling Pathway Regulation Of Complement Activation Fc-gamma Receptor Signaling Pathway Involved In Phagocytosis Defense Response To Bacterium Innate Immune Response B Cell Receptor Signaling Pathway Positive Regulation Of B Cell Activation
Pathways		Regulation of HSF1-mediated heat shock response
Drugs
Diseases
GWAS		anorexia nervosa, attention-deficit/hyperactivity disorder, autism spectrum disorder, bipolar disorder, major depression, obsessive-compulsive disorder, schizophrenia, or Tourette syndrome (pleiotropy) ( 31835028) Autism spectrum disorder or schizophrenia ( 28540026) Body mass index ( 26426971) Brain morphology (MOSTest) ( 32665545) Broad depression or schizophrenia ( 30626913) Depression ( 29700475) Schizophrenia ( 25056061)
Interacting Genes		19 interacting genes: BANP CDCA7L CIRBP DES EFEMP1 FAM118B GOLGA6A HSPA4 KASH5 KRTAP5-4 LRRK1 MAD1L1 PINK1 PRKN SNCA STUB1 THAP1 TP53 TRIM27
Entrez ID		9529	3503
HPRD ID		04862	11757
Ensembl ID		ENSG00000166170	ENSG00000211892
Uniprot IDs		A0A024R6M6 Q9UL15
PDB IDs		2D9D 3A8Y
Enriched GO Terms of Interacting Partners?
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