PPIG and SLU7

Data Source:
BioGRID (two hybrid, two hybrid)

		PPIG	SLU7
Description		peptidylprolyl isomerase G	SLU7 homolog, splicing factor
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GO Annotations	Cellular Component	Nucleus Nucleoplasm Cytoplasm Cytosol Nuclear Matrix Nuclear Speck Intracellular Membrane-bounded Organelle	Nucleus Nucleoplasm Spliceosomal Complex Cytoplasm Cytosol Membrane Nuclear Speck Small Nuclear Ribonucleoprotein Complex Intracellular Membrane-bounded Organelle Catalytic Step 2 Spliceosome
	Molecular Function	RNA Binding Peptidyl-prolyl Cis-trans Isomerase Activity Protein Binding Cyclosporin A Binding	Second Spliceosomal Transesterification Activity Protein Binding Zinc Ion Binding Pre-mRNA 3'-splice Site Binding
	Biological Process	Protein Peptidyl-prolyl Isomerization Protein Folding RNA Splicing	RNA Splicing, Via Transesterification Reactions Alternative MRNA Splicing, Via Spliceosome MRNA 3'-splice Site Recognition MRNA Splicing, Via Spliceosome RNA Export From Nucleus MRNA Export From Nucleus Intracellular Protein Transport RNA Splicing MRNA 3'-end Processing Cellular Response To Heat
Pathways			Transport of Mature mRNA derived from an Intron-Containing Transcript mRNA Splicing - Major Pathway mRNA 3'-end processing RNA Polymerase II Transcription Termination
Drugs		Proline
Diseases
GWAS			Asthma ( 32296059) Common carotid intima-media thickness ( 29206233)
Interacting Genes		27 interacting genes: BEND7 CACNA1A CEP70 CLK1 DAB1 DACH1 FHL3 KCTD6 LGALS3 NKAP PCBP1 PNMA2 PNN POLR2A PPCDC PRPF38A PRPF40A RBM39 SLU7 SMN1 SMN2 SP1 TFCP2 THAP1 TRIM54 YWHAG ZCCHC10	27 interacting genes: AIMP2 BAG2 CCDC85B CEP70 DEF6 FHL3 GOLGA2 GTF2I IKBKG JMJD6 KDM1A KRT40 LMNA LONRF1 LZTS2 MCC NFKBID NSD3 PCBP2 PIBF1 PPIG PPIL3 PRMT5 PRMT6 TEPSIN THAP1 ZCCHC10
Entrez ID		9360	10569
HPRD ID		12083	12074
Ensembl ID		ENSG00000138398	ENSG00000164609
Uniprot IDs		Q13427	O95391
PDB IDs		2GW2 2WFI 2WFJ 5YZG	5XJC 6ICZ 6QDV
Enriched GO Terms of Interacting Partners?
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