KCNAB3 and ZBTB14

Data Source:
HPRD (two hybrid, in vivo, in vitro)

		KCNAB3	ZBTB14
Description		potassium voltage-gated channel subfamily A regulatory beta subunit 3	zinc finger and BTB domain containing 14
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Cytoplasm Plasma Membrane Voltage-gated Potassium Channel Complex	Nucleus Nucleoplasm Nucleolus Cytosol Aggresome
	Molecular Function	Aldo-keto Reductase (NADP) Activity Voltage-gated Potassium Channel Activity Protein Binding Potassium Channel Regulator Activity Ion Channel Binding	Transcription Regulatory Region Sequence-specific DNA Binding RNA Polymerase II Cis-regulatory Region Sequence-specific DNA Binding DNA-binding Transcription Repressor Activity, RNA Polymerase II-specific DNA-binding Transcription Factor Activity Protein Binding Sequence-specific DNA Binding Metal Ion Binding Sequence-specific Double-stranded DNA Binding
	Biological Process	Potassium Ion Transport Potassium Ion Transmembrane Transport Regulation Of Potassium Ion Transmembrane Transport	Negative Regulation Of Transcription By RNA Polymerase II Kidney Development Heart Valve Development Cardiac Septum Development Regulation Of Transcription By RNA Polymerase II Negative Regulation Of Transcription, DNA-templated Coronary Vasculature Development
Pathways		Voltage gated Potassium channels
Drugs
Diseases
GWAS		Diastolic blood pressure x smoking status (current vs non-current) interaction (2df test) ( 29455858) Diastolic blood pressure x smoking status (ever vs never) interaction (2df test) ( 29455858) Refractive error ( 32231278) Systolic blood pressure x smoking status (current vs non-current) interaction (2df test) ( 29455858) Systolic blood pressure x smoking status (ever vs never) interaction (2df test) ( 29455858)	Cerebral amyloid deposition (PET imaging) ( 26252872)
Interacting Genes		4 interacting genes: APP GMDS NEDD4L PLEKHF2	50 interacting genes: AP1M1 ATP5PO ATRIP BAZ2B BYSL C2orf68 CAPN6 CBX8 CDK16 CDKL3 CEP19 DDX6 EAF1 EIF1AD ENKD1 EPM2AIP1 FAM161A FAM90A1 GORASP2 INTS3 KAT5 MAD2L1BP MFAP1 MORF4L2 MRPL11 NAA10 NAA11 PIN1 PNKP POLR2L PRMT1 RNASEH2B RNPS1 RPA1 RPA2 RPL9 RPS25 RPS7 SCNM1 SDCBP SNRPB2 SYT16 TCEANC TRIM55 TSTD2 TXN2 WNT9A ZBTB21 ZCCHC10 ZMAT2
Entrez ID		9196	7541
HPRD ID		04983	03674
Ensembl ID		ENSG00000170049	ENSG00000198081
Uniprot IDs		O43448	B2R850 O43829
PDB IDs
Enriched GO Terms of Interacting Partners?
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