ZNF804A and DNAJC10

Data Source:
BioGRID (proximity labelling technology)

		ZNF804A	DNAJC10
Description		zinc finger protein 804A	DnaJ heat shock protein family (Hsp40) member C10
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Nucleus Cytoplasm Plasma Membrane Growth Cone Neuronal Cell Body Dendritic Spine Dendritic Shaft Presynapse Postsynapse Dendritic Microtubule	Endoplasmic Reticulum Endoplasmic Reticulum Lumen Membrane Endoplasmic Reticulum Chaperone Complex
	Molecular Function	Molecular_function Metal Ion Binding	ATPase Activator Activity Protein Binding Protein Disulfide Oxidoreductase Activity Disulfide Oxidoreductase Activity Oxidoreductase Activity, Acting On A Sulfur Group Of Donors, Disulfide As Acceptor Hsp70 Protein Binding Chaperone Binding ATPase Binding Misfolded Protein Binding
	Biological Process	Positive Regulation Of Gene Expression Regulation Of Neuron Projection Development Positive Regulation Of Neuron Projection Development Positive Regulation Of Dendritic Spine Maintenance	Negative Regulation Of Protein Phosphorylation Ubiquitin-dependent ERAD Pathway Positive Regulation Of ATPase Activity Protein Folding In Endoplasmic Reticulum Response To Endoplasmic Reticulum Stress Intrinsic Apoptotic Signaling Pathway In Response To Endoplasmic Reticulum Stress
Pathways
Drugs
Diseases
GWAS		Alzheimer disease and age of onset ( 26830138) anorexia nervosa, attention-deficit/hyperactivity disorder, autism spectrum disorder, bipolar disorder, major depression, obsessive-compulsive disorder, schizophrenia, or Tourette syndrome (pleiotropy) ( 31835028) Autism spectrum disorder or schizophrenia ( 28540026) Autism spectrum disorder, attention deficit-hyperactivity disorder, bipolar disorder, major depressive disorder, and schizophrenia (combined) ( 23453885) Bipolar disorder ( 31043756) Bipolar disorder lithium response (continuous) or schizophrenia ( 29121268) Breakfast cereal skipping frequency ( 31190057) Breakfast skipping ( 31190057) Broad depression or schizophrenia ( 30626913) Cervical artery dissection ( 25420145) Chronotype ( 30696823) Cognitive ability, years of educational attainment or schizophrenia (pleiotropy) ( 31374203) Dentures ( 31235808) Feeling hurt ( 29500382) Loneliness (linear analysis) ( 27629369) Neurociticism ( 29500382) Neuroticism ( 29255261) Number of decayed, missing and filled tooth surfaces or use of dentures ( 31235808) Obesity-related traits ( 23251661) Schizophrenia ( 28991256 25056061 18677311 29483656 30285260) Systolic blood pressure ( 30224653)	Blood protein levels ( 30072576) Night sleep phenotypes ( 27126917) Pulmonary arterial hypertension ( 29088834) Waist-to-hip circumference ratio (dietary energy interaction) ( 23192594)
Interacting Genes		2 interacting genes: ATXN1 SPP1	4 interacting genes: HSPA5 MAGEA11 PTEN SQSTM1
Entrez ID		91752	54431
HPRD ID		12804	09722
Ensembl ID		ENSG00000170396	ENSG00000077232
Uniprot IDs		Q7Z570	Q8IXB1
PDB IDs
Enriched GO Terms of Interacting Partners?
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