RSAD2 and UBE4A

Data Source:
BioGRID (affinity chromatography technology, pull down)

		RSAD2	UBE4A
Description		radical S-adenosyl methionine domain containing 2	ubiquitination factor E4A
Image		No pdb structure
GO Annotations	Cellular Component	Fibrillar Center Mitochondrion Mitochondrial Outer Membrane Mitochondrial Inner Membrane Endoplasmic Reticulum Endoplasmic Reticulum Membrane Golgi Apparatus Lipid Droplet	Ubiquitin Ligase Complex Nucleus Cytoplasm
	Molecular Function	Catalytic Activity Protein Binding Protein Self-association Metal Ion Binding 4 Iron, 4 Sulfur Cluster Binding	Protein Binding Ubiquitin-ubiquitin Ligase Activity
	Biological Process	Response To Virus Viral Process Positive Regulation Of Toll-like Receptor 7 Signaling Pathway Positive Regulation Of Toll-like Receptor 9 Signaling Pathway CD4-positive, Alpha-beta T Cell Activation CD4-positive, Alpha-beta T Cell Differentiation Negative Regulation Of Viral Genome Replication Negative Regulation Of Protein Secretion Positive Regulation Of Immune Response Defense Response To Virus Type I Interferon Signaling Pathway Positive Regulation Of T-helper 2 Cell Cytokine Production	Protein Polyubiquitination Ubiquitin-dependent Protein Catabolic Process Ubiquitin-dependent ERAD Pathway
Pathways		Interferon alpha/beta signaling	Antigen processing: Ubiquitination & Proteasome degradation
Drugs
Diseases
GWAS			Celiac disease and Rheumatoid arthritis ( 26546613) Fat distribution (HIV) ( 21897333)
Interacting Genes		6 interacting genes: APOC1 APOC2 APOC4 RHBDD2 UBE2D1 UBE4A	13 interacting genes: CASP6 EPHA2 GZMB IP6K1 MAVS PTTG1 RSAD2 SLA UBE2D1 UBE2D2 UBE2D3 UBE2D4 VCP
Entrez ID		91543	9354
HPRD ID		07423	06793
Ensembl ID		ENSG00000134321	ENSG00000110344
Uniprot IDs		Q8WXG1	Q14139
PDB IDs			1WGM
Enriched GO Terms of Interacting Partners?
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