TMEM67 and INTS8

Data Source:
BioGRID (affinity chromatography technology)

		TMEM67	INTS8
Description		transmembrane protein 67	integrator complex subunit 8
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Endoplasmic Reticulum Membrane Centrosome Integral Component Of Membrane Cytoplasmic Vesicle Membrane Ciliary Transition Zone MKS Complex Ciliary Membrane	Nucleoplasm Integrator Complex
	Molecular Function	Protein Binding Filamin Binding Unfolded Protein Binding	Protein Binding
	Biological Process	Negative Regulation Of Centrosome Duplication Ubiquitin-dependent ERAD Pathway Cilium Assembly Ciliary Basal Body-plasma Membrane Docking	SnRNA Processing SnRNA 3'-end Processing SnRNA Transcription By RNA Polymerase II
Pathways		Anchoring of the basal body to the plasma membrane	RNA polymerase II transcribes snRNA genes RNA polymerase II transcribes snRNA genes
Drugs
Diseases		Joubert syndrome COACH syndrome Nephronophthisis-medullary cystic kidney disease, including; Nephronophthisis (NPH) ; Nephronophthisis-like nephropathy 1; Medullary cystic kidney disease 1; Medullary cystic kidney disease 2 (MSKD2) Meckel syndrome (MKS); Meckel-Gruber syndrome
GWAS			Mean corpuscular hemoglobin ( 32888494) Mean corpuscular volume ( 32888494) Molybdenum levels ( 26025379) Multiple sclerosis ( 31604244) Type 2 diabetes ( 25102180)
Interacting Genes		2 interacting genes: MKS1 UBQLN1	1 interacting genes: CTDP1
Entrez ID		91147	55656
HPRD ID		11324	08626
Ensembl ID		ENSG00000164953	ENSG00000164941
Uniprot IDs		Q5HYA8	Q75QN2
PDB IDs
Enriched GO Terms of Interacting Partners?
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