SYS1 and IL3RA

Data Source:
BioGRID (two hybrid)

		SYS1	IL3RA
Description		SYS1 golgi trafficking protein	interleukin 3 receptor subunit alpha
Image		No pdb structure
GO Annotations	Cellular Component	Trans-Golgi Network Cytosol Integral Component Of Golgi Membrane Trans-Golgi Network Membrane	Plasma Membrane External Side Of Plasma Membrane Integral Component Of Membrane Receptor Complex
	Molecular Function	Protein Binding	Cytokine Receptor Activity Interleukin-3 Receptor Activity Protein Binding Cytokine Binding
	Biological Process	Golgi To Endosome Transport Protein Localization To Golgi Apparatus Golgi To Plasma Membrane Protein Transport	MAPK Cascade Cytokine-mediated Signaling Pathway Cellular Response To Interleukin-3 Interleukin-3-mediated Signaling Pathway
Pathways		Retrograde transport at the Trans-Golgi-Network	Interleukin-3, Interleukin-5 and GM-CSF signaling RAF/MAP kinase cascade Interleukin receptor SHC signaling
Drugs			Sargramostim Tagraxofusp
Diseases
GWAS		Free cholesterol levels in large HDL ( 29084231) Large HDL particle concentration ( 29084231) Malaria ( 31844061) Mean diameter of HDL particles ( 29084231) Phospholipid levels in large HDL ( 29084231)	Schizophrenia ( 17522711)
Interacting Genes		20 interacting genes: BTNL9 EBP ELOVL5 ERGIC3 FCER1G GLP1R HSD17B11 IL3RA KIR3DL3 MCFD2 MGST3 MRPS18B PSCA PVR SDCBP SLC30A8 SLC35C2 TM4SF19 TMEM248 TNFSF14	32 interacting genes: BMP10 C2CD2L CDC25A CDK1 CISH CLDN19 CSF2 CSF2RB EMP3 FOXP1 GIMAP1 GNA12 IL3 JAGN1 JAK1 JAK2 LNX1 NINJ2 NR0B2 PAQR5 PPP1CC SAE1 SERP1 SGK2 SMAGP SYS1 TMEM128 TMEM147 TMEM254 TMEM65 TRARG1 VAMP5
Entrez ID		90196	3563
HPRD ID			02392
Ensembl ID		ENSG00000204070	ENSG00000185291
Uniprot IDs		Q8N2H4	P26951
PDB IDs			4JZJ 5UV8 5UWC 6NMY
Enriched GO Terms of Interacting Partners?
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