TNFSF9 and CLPP

Data Source:
BioGRID (affinity chromatography technology)

		TNFSF9	CLPP
Description		TNF superfamily member 9	caseinolytic mitochondrial matrix peptidase proteolytic subunit
Image
GO Annotations	Cellular Component	Extracellular Space Plasma Membrane Integral Component Of Membrane	Mitochondrion Mitochondrial Matrix Endopeptidase Clp Complex
	Molecular Function	Signaling Receptor Binding Cytokine Activity Tumor Necrosis Factor Receptor Binding Tumor Necrosis Factor Receptor Superfamily Binding	Endopeptidase Activity ATP-dependent Peptidase Activity Serine-type Endopeptidase Activity Protein Binding Peptidase Activity Identical Protein Binding ATPase Binding
	Biological Process	Immune Response Cell-cell Signaling Tumor Necrosis Factor-mediated Signaling Pathway Positive Regulation Of Activated T Cell Proliferation Regulation Of T Cell Proliferation Regulation Of Apoptotic Process Positive Regulation Of Cytotoxic T Cell Differentiation	Protein Quality Control For Misfolded Or Incompletely Synthesized Proteins Membrane Protein Proteolysis Proteolysis Involved In Cellular Protein Catabolic Process
Pathways		TNFs bind their physiological receptors
Drugs			N-Formylmethionine
Diseases
GWAS		Metabolite levels ( 23823483)
Interacting Genes		3 interacting genes: TNFRSF9 TRAF1 TRAF2	16 interacting genes: ABI2 C14orf119 CLPX DTX2 EFEMP1 EFEMP2 GRN KRTAP10-1 NUTF2 P4HA3 PLSCR4 PPP2CA PSMB1 RBPMS TNPO3 TRIM54
Entrez ID		8744	8192
HPRD ID		05861	03074
Ensembl ID		ENSG00000125657	ENSG00000125656
Uniprot IDs		A0A0U5J8I0 P41273	Q16740
PDB IDs		2X29 6A3V 6BWV 6CPR 6CU0 6D3N 6FIB 6MGE 6MGP	1TG6 6BBA 6DL7 6H23
Enriched GO Terms of Interacting Partners?
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