CDC14A and PTK7

Data Source:
BioGRID (two hybrid)

		CDC14A	PTK7
Description		cell division cycle 14A	protein tyrosine kinase 7 (inactive)
Image		No pdb structure
GO Annotations	Cellular Component	Spindle Pole Nucleoplasm Nucleolus Cytoplasm Centrosome Cytosol Nuclear Body Stereocilium Tip Kinocilium Mitotic Spindle Kinociliary Basal Body	Plasma Membrane Integral Component Of Plasma Membrane Cell-cell Junction Focal Adhesion
	Molecular Function	Protein Serine/threonine Phosphatase Activity Protein Tyrosine Phosphatase Activity Protein Binding Protein Tyrosine/serine/threonine Phosphatase Activity Protein Serine Phosphatase Activity Protein Threonine Phosphatase Activity	Protein Kinase Activity Protein Binding ATP Binding Cell Adhesion Molecule Binding Coreceptor Activity Involved In Wnt Signaling Pathway, Planar Cell Polarity Pathway
	Biological Process	Microtubule Cytoskeleton Organization Mitotic Cell Cycle Regulation Of Exit From Mitosis Sensory Perception Of Sound Positive Regulation Of Cytokinesis Peptidyl-tyrosine Dephosphorylation Cell Division Cilium Assembly Mitotic Cell Cycle Arrest	Establishment Of Planar Polarity Kidney Development Ventricular Septum Development Axis Elongation Protein Phosphorylation Cell Adhesion Signal Transduction Positive Regulation Of Neuron Projection Development Cell Migration Actin Cytoskeleton Reorganization Wound Healing Establishment Of Epithelial Cell Apical/basal Polarity Convergent Extension Lung-associated Mesenchyme Development Regulation Of Canonical Wnt Signaling Pathway Coronary Vasculature Development Cellular Response To Retinoic Acid Cochlea Morphogenesis Planar Cell Polarity Pathway Involved In Neural Tube Closure Positive Regulation Of Canonical Wnt Signaling Pathway
Pathways		Conversion from APC/C:Cdc20 to APC/C:Cdh1 in late anaphase MAPK6/MAPK4 signaling
Drugs
Diseases
GWAS		Estimated glomerular filtration rate ( 31152163 31015462) Systolic blood pressure x educational attainment (some college) interaction (2df) ( 32372009)	Coronary artery disease ( 29212778)
Interacting Genes		15 interacting genes: AATK ATPAF2 BRAP C14orf119 CDC25B CDC6 CHRM1 FZR1 KIF20A LMTK2 PLK1 POLR2A PTK7 ROR2 TP53	38 interacting genes: CDC14A CLNK CTDSP2 DUSP10 DUSP14 DUSP15 DUSP18 DUSP19 DUSP21 DUSP26 DUSP29 ERBB2 ILKAP KRTAP1-3 KRTAP10-8 MDFI MTMR1 MTMR10 MTMR6 MTMR9 MTUS2 NBPF19 NOTCH2NLA PPM1A PPM1B PPM1F PPM1K PPP3CA PPP3CB PTEN PTPN11 PTPN12 PTPN6 PTPN7 PTPRR STYX TPTE TPTE2
Entrez ID		8556	5754
HPRD ID		04614	03534
Ensembl ID		ENSG00000079335	ENSG00000112655
Uniprot IDs		A0A0U1RQX7 A0A2R8YDJ8 B4DY86 Q59EF4 Q9UNH5	Q13308
PDB IDs			6VG3
Enriched GO Terms of Interacting Partners?
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