DCLK3 and TRANK1

Data Source:
BioGRID (biochemical)

		DCLK3	TRANK1
Description		doublecortin like kinase 3	tetratricopeptide repeat and ankyrin repeat containing 1
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Nucleus Cytoplasm
	Molecular Function	Protein Kinase Activity ATP Binding Protein Serine Kinase Activity Protein Threonine Kinase Activity
	Biological Process	Peptidyl-serine Phosphorylation
Pathways
Drugs		Fostamatinib
Diseases
GWAS		anorexia nervosa, attention-deficit/hyperactivity disorder, autism spectrum disorder, bipolar disorder, major depression, obsessive-compulsive disorder, schizophrenia, or Tourette syndrome (pleiotropy) ( 31835028) Chronotype ( 30696823) Morning person ( 30696823) Schizophrenia ( 28991256) Takayasu arteritis ( 25604533) White matter hyperintensity volume ( 32062564)	anorexia nervosa, attention-deficit/hyperactivity disorder, autism spectrum disorder, bipolar disorder, major depression, obsessive-compulsive disorder, schizophrenia, or Tourette syndrome (pleiotropy) ( 31835028) Apolipoprotein A1 levels ( 32203549) Autism spectrum disorder or schizophrenia ( 28540026) Bipolar disorder ( 22182935 28115744 24618891 31043756 28072414 27329760) Bipolar disorder with mood-incongruent psychosis ( 23092984) Bipolar I disorder ( 31043756) Chronotype ( 30696823) Electrocardiogram morphology (amplitude at temporal datapoints) ( 32916098) HDL cholesterol ( 30275531) HDL cholesterol levels ( 32203549) Iris color (L* coordinate) ( 29109912) Mean platelet volume ( 32888494) Morning person ( 30696823) Platelet distribution width ( 27863252) Pulse pressure ( 30224653) Schizophrenia ( 28991256 25056061 29483656 30285260) Schizophrenia or bipolar disorder ( 24280982) Subjective response to lithium treatment ( 26503763) Triglycerides ( 30275531)
Interacting Genes
Entrez ID		85443	9881
HPRD ID		19338	19247
Ensembl ID		ENSG00000163673	ENSG00000168016
Uniprot IDs		B3KVM3 Q9C098	A0A2R8YEM9 O15050
PDB IDs
Enriched GO Terms of Interacting Partners?
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