RAE1 and CASS4

Data Source:
BioGRID (biochemical)

		RAE1	CASS4
Description		ribonucleic acid export 1	Cas scaffold protein family member 4
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GO Annotations	Cellular Component	Fibrillar Center Nucleus Nuclear Envelope Nuclear Pore Nucleoplasm Cytoplasm Host Cell Mitotic Spindle Pole	Cytoplasm Cytoskeleton Plasma Membrane Focal Adhesion
	Molecular Function	RNA Binding Protein Binding Microtubule Binding Ubiquitin Binding	Protein Tyrosine Kinase Binding
	Biological Process	Transcription-dependent Tethering Of RNA Polymerase II Gene DNA At Nuclear Periphery Regulation Of Glycolytic Process RNA Export From Nucleus MRNA Export From Nucleus TRNA Export From Nucleus Cell Cycle Viral Process Protein Sumoylation Viral Transcription Cell Division Regulation Of Mitotic Spindle Organization Regulation Of Gene Silencing By MiRNA Intracellular Transport Of Virus Regulation Of Cellular Response To Heat	Cell Adhesion Transmembrane Receptor Protein Tyrosine Kinase Signaling Pathway Cell Migration Positive Regulation Of Cell Migration Positive Regulation Of Protein Kinase B Signaling Positive Regulation Of Protein Tyrosine Kinase Activity Actin Filament Reorganization Positive Regulation Of Substrate Adhesion-dependent Cell Spreading
Pathways		ISG15 antiviral mechanism Transport of the SLBP independent Mature mRNA Transport of the SLBP Dependant Mature mRNA Transport of Mature mRNA Derived from an Intronless Transcript Transport of Mature mRNA derived from an Intron-Containing Transcript Rev-mediated nuclear export of HIV RNA Transport of Ribonucleoproteins into the Host Nucleus NS1 Mediated Effects on Host Pathways Viral Messenger RNA Synthesis NEP/NS2 Interacts with the Cellular Export Machinery Regulation of Glucokinase by Glucokinase Regulatory Protein Nuclear import of Rev protein Vpr-mediated nuclear import of PICs snRNP Assembly SUMOylation of DNA damage response and repair proteins SUMOylation of ubiquitinylation proteins Nuclear Pore Complex (NPC) Disassembly Regulation of HSF1-mediated heat shock response SUMOylation of SUMOylation proteins SUMOylation of chromatin organization proteins SUMOylation of RNA binding proteins SUMOylation of DNA replication proteins SUMOylation of DNA replication proteins Transcriptional regulation by small RNAs Defective TPR may confer susceptibility towards thyroid papillary carcinoma (TPC) tRNA processing in the nucleus HCMV Early Events HCMV Late Events
Drugs
Diseases
GWAS			Alzheimer's disease (late onset) ( 30617256 24162737) Alzheimer's disease or family history of Alzheimer's disease ( 30617256) Cognitive decline (age-related) ( 28078323) Family history of Alzheimer's disease ( 30617256) Platelet count ( 32888494 27863252) Plateletcrit ( 32888494 27863252) Refractive astigmatism ( 25367360)
Interacting Genes		9 interacting genes: BDKRB1 BUB1 DDX24 HTR2B KLRC4 KLRK1 NUMA1 NUP98 NXF1	5 interacting genes: ANKS1B CDC42EP2 FHL3 HSF2BP ZYX
Entrez ID		8480	57091
HPRD ID		11939	09842
Ensembl ID		ENSG00000101146	ENSG00000087589
Uniprot IDs		P78406	B4DII4 Q9NQ75
PDB IDs		3MMY 4OWR	2CRE
Enriched GO Terms of Interacting Partners?
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