PCGF1 and CD244

Data Source:
BioGRID (proximity labelling technology)

		PCGF1	CD244
Description		polycomb group ring finger 1	CD244 molecule
Image			No pdb structure
GO Annotations	Cellular Component	Nucleus Nucleoplasm PcG Protein Complex PRC1 Complex	Plasma Membrane External Side Of Plasma Membrane Integral Component Of Membrane
	Molecular Function	Protein Binding Protein C-terminus Binding Metal Ion Binding Promoter-specific Chromatin Binding	Protein Binding Signaling Receptor Activity MHC Class I Protein Binding
	Biological Process	Negative Regulation Of Transcription By RNA Polymerase II Chromatin Silencing Regulation Of Transcription, DNA-templated Histone H2A Monoubiquitination Histone H2A-K119 Monoubiquitination	Adaptive Immune Response Natural Killer Cell Activation Involved In Immune Response Signal Transduction Positive Regulation Of Interferon-gamma Production Positive Regulation Of Interleukin-8 Production Innate Immune Response Leukocyte Migration Positive Regulation Of Inositol Phosphate Biosynthetic Process Positive Regulation Of Granzyme B Production
Pathways			Cell surface interactions at the vascular wall
Drugs
Diseases
GWAS			Blood protein levels ( 28240269) Crohn's disease ( 21102463) Inflammatory bowel disease ( 23128233) Lymphocyte percentage of white cells ( 32888494) Neutrophil percentage of white cells ( 32888494) White blood cell count ( 32888494)
Interacting Genes		12 interacting genes: BCOR CALCOCO2 CBX6 CBX7 FCHO1 MUC7 PCGF5 RNF125 RNF2 TRIM55 UBE2D3 UBE2U	5 interacting genes: ARHGEF7 CD247 CD48 LAT SH2D1B
Entrez ID		84759	51744
HPRD ID		11404	16121
Ensembl ID		ENSG00000115289	ENSG00000122223
Uniprot IDs		Q9BSM1	Q9BZW8
PDB IDs		4HPL 4HPM 5JH5
Enriched GO Terms of Interacting Partners?
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