KAT8 and CLEC4A

Data Source:
BioGRID (affinity chromatography technology)

		KAT8	CLEC4A
Description		lysine acetyltransferase 8	C-type lectin domain family 4 member A
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GO Annotations	Cellular Component	Histone Acetyltransferase Complex Kinetochore Nucleus Nucleoplasm Nuclear Matrix MLL1 Complex MSL Complex	Plasma Membrane Integral Component Of Plasma Membrane
	Molecular Function	Transcription Coregulator Activity Histone Acetyltransferase Activity Protein Binding Transcription Factor Binding Acetyltransferase Activity Enzyme Binding Methylated Histone Binding Histone Binding Histone Acetyltransferase Activity (H4-K5 Specific) Histone Acetyltransferase Activity (H4-K8 Specific) Metal Ion Binding Histone Acetyltransferase Activity (H4-K16 Specific)	Transmembrane Signaling Receptor Activity Calcium Ion Binding Mannose Binding Carbohydrate Binding
	Biological Process	Regulation Of Autophagy Histone Acetylation Myeloid Cell Differentiation Histone H4-K5 Acetylation Histone H4-K8 Acetylation Histone H4-K16 Acetylation Negative Regulation Of Transcription, DNA-templated Positive Regulation Of Transcription, DNA-templated Positive Regulation Of Transcription By RNA Polymerase II	Negative Regulation Of Cytokine Production Stimulatory C-type Lectin Receptor Signaling Pathway Adaptive Immune Response Plasmacytoid Dendritic Cell Antigen Processing And Presentation Cell Adhesion Cell Surface Receptor Signaling Pathway Viral Process Negative Regulation Of Tumor Necrosis Factor Production CD8-positive, Alpha-beta T Cell Activation Antigen Processing And Presentation Of Exogenous Peptide Antigen Via MHC Class I Innate Immune Response
Pathways		HATs acetylate histones	Dectin-2 family
Drugs
Diseases
GWAS		Alzheimer's disease or family history of Alzheimer's disease ( 30617256) Bipolar disorder ( 31043756) Bipolar I disorder ( 31043756) Body mass index ( 25673413) Family history of Alzheimer's disease ( 30617256) Parkinson's disease ( 28892059) Triglyceride levels ( 32154731)
Interacting Genes		12 interacting genes: ATM BAZ2A FOXP3 H4C1 KANSL1 KMT2A MSL3 PAF1 PLAU RNF2 TP53 TP53BP1	2 interacting genes: LMNA PTPN6
Entrez ID		84148	50856
HPRD ID		11381	05604
Ensembl ID		ENSG00000103510	ENSG00000111729
Uniprot IDs		Q9H7Z6	Q9UMR7
PDB IDs		2GIV 2PQ8 2Y0M 3QAH 3TOA 3TOB 4DNC 5H43 5J8C 5J8F 5WCI 6BA2 6BA4 6CT2 6OIN 6OIO 6OIP 6OIQ 6OIR 6OWH 6OWI 6PD8 6PD9 6PDA 6PDB 6PDC 6PDD 6PDE 6PDF 6PDG 7CMR	5B1W 5B1X
Enriched GO Terms of Interacting Partners?
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