KAT8 and PRRT2

Data Source:
BioGRID (affinity chromatography technology)

		KAT8	PRRT2
Description		lysine acetyltransferase 8	proline rich transmembrane protein 2
Image			No pdb structure
GO Annotations	Cellular Component	Histone Acetyltransferase Complex Kinetochore Nucleus Nucleoplasm Nuclear Matrix MLL1 Complex MSL Complex	Plasma Membrane Synaptic Vesicle Membrane Integral Component Of Membrane Synaptic Vesicle Membrane Vesicle Presynaptic Membrane Dendritic Spine Axon Terminus Presynapse Postsynaptic Density Membrane
	Molecular Function	Transcription Coregulator Activity Histone Acetyltransferase Activity Protein Binding Transcription Factor Binding Acetyltransferase Activity Enzyme Binding Methylated Histone Binding Histone Binding Histone Acetyltransferase Activity (H4-K5 Specific) Histone Acetyltransferase Activity (H4-K8 Specific) Metal Ion Binding Histone Acetyltransferase Activity (H4-K16 Specific)	Protein Binding Syntaxin-1 Binding
	Biological Process	Regulation Of Autophagy Histone Acetylation Myeloid Cell Differentiation Histone H4-K5 Acetylation Histone H4-K8 Acetylation Histone H4-K16 Acetylation Negative Regulation Of Transcription, DNA-templated Positive Regulation Of Transcription, DNA-templated Positive Regulation Of Transcription By RNA Polymerase II	Synaptic Vesicle Fusion To Presynaptic Active Zone Membrane Negative Regulation Of SNARE Complex Assembly Neuromuscular Process Controlling Posture Negative Regulation Of Short-term Synaptic Potentiation
Pathways		HATs acetylate histones
Drugs
Diseases
GWAS		Alzheimer's disease or family history of Alzheimer's disease ( 30617256) Bipolar disorder ( 31043756) Bipolar I disorder ( 31043756) Body mass index ( 25673413) Family history of Alzheimer's disease ( 30617256) Parkinson's disease ( 28892059) Triglyceride levels ( 32154731)
Interacting Genes		12 interacting genes: ATM BAZ2A FOXP3 H4C1 KANSL1 KMT2A MSL3 PAF1 PLAU RNF2 TP53 TP53BP1	8 interacting genes: AQP6 F2RL1 GPRC5D MFSD14B SLC10A6 SMIM5 SNAP25 TLCD4
Entrez ID		84148	112476
HPRD ID		11381	13995
Ensembl ID		ENSG00000103510	ENSG00000167371
Uniprot IDs		Q9H7Z6	Q7Z6L0
PDB IDs		2GIV 2PQ8 2Y0M 3QAH 3TOA 3TOB 4DNC 5H43 5J8C 5J8F 5WCI 6BA2 6BA4 6CT2 6OIN 6OIO 6OIP 6OIQ 6OIR 6OWH 6OWI 6PD8 6PD9 6PDA 6PDB 6PDC 6PDD 6PDE 6PDF 6PDG 7CMR
Enriched GO Terms of Interacting Partners?
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