Description |
splA/ryanodine receptor domain and SOCS box containing 1 |
nitric oxide synthase 2 |
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Cellular Component |
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Molecular Function |
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Biological Process |
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Pathways |
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Drugs |
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- Arginine
- Citrulline
- Minocycline
- Miconazole
- Dexamethasone
- N,N-dimethylarginine
- 4R-Fluoro-N6-ethanimidoyl-L-lysine
- 3-Bromo-7-Nitroindazole
- N-[3-(aminomethyl)benzyl]acetamidine
- 7-Nitroindazole
- S-Ethylisothiourea
- Thiocoumarin
- N-omega-propyl-L-arginine
- 6-Nitroindazole
- N(5)-[(hydroxyamino)(imino)methyl]-L-ornithine
- Imidazole
- N-(4-{2-[(3-chlorobenzyl)amino]ethyl}phenyl)thiophene-2-carboximidamide
- Thiocitrulline
- L-erythro-7,8-dihydrobiopterin
- 5-Nitroindazole
- KD7040
- Fenoxaprop-ethyl
- Pimagedine
- 5-(4'-AMINO-1'-ETHYL-5',8'-DIFLUORO-1'H-SPIRO[PIPERIDINE-4,2'-QUINAZOLINE]-1-YLCARBONYL)PICOLINONITRILE
- N-[2-(1,3-BENZODIOXOL-5-YL)ETHYL]-1-[2-(1H-IMIDAZOL-1-YL)-6-METHYLPYRIMIDIN-4-YL]-D-PROLINAMIDE
- 4-({4-[(4-methoxypyridin-2-yl)amino]piperidin-1-yl}carbonyl)benzonitrile
- (2S)-2-methyl-2,3-dihydrothieno[2,3-f][1,4]oxazepin-5-amine
- (3R)-3-[(1,2,3,4-tetrahydroisoquinolin-7-yloxy)methyl]-2,3-dihydrothieno[2,3-f][1,4]oxazepin-5-amine
- 4-(1,3-BENZODIOXOL-5-YLOXY)-2-[4-(1H-IMIDAZOL-1-YL)PHENOXY]PYRIMIDINE
- (3S)-1-(1,3-BENZODIOXOL-5-YLMETHYL)-3-[4-(1H-IMIDAZOL-1-YL)PHENOXY]PIPERIDINE
- 4-(1,3-BENZODIOXOL-5-YLOXY)-2-[4-(1H-IMIDAZOL-1-YL)PHENOXY]-6-METHYLPYRIMIDINE
- ETHYL 4-[(4-CHLOROPYRIDIN-2-YL)AMINO]PIPERIDINE-1-CARBOXYLATE
- N-[2-(4-AMINO-5,8-DIFLUORO-1,2-DIHYDROQUINAZOLIN-2-YL)ETHYL]-3-FURAMIDE
- ETHYL 4-[(4-METHYLPYRIDIN-2-YL)AMINO]PIPERIDINE-1-CARBOXYLATE
- N-[2-(6-AMINO-4-METHYLPYRIDIN-2-YL)ETHYL]-4-CYANOBENZAMIDE
- 1-(6-CYANO-3-PYRIDYLCARBONYL)-5',8'-DIFLUOROSPIRO[PIPERIDINE-4,2'(1'H)-QUINAZOLINE]-4'-AMINE
- 4-(1H-IMIDAZOL-1-YL)PHENOL
- 1-[4-(AMINOMETHYL)BENZOYL]-5'-FLUORO-1'H-SPIRO[PIPERIDINE-4,2'-QUINAZOLIN]-4'-AMINE
- Triflusal
- Levamlodipine
- Dipyrithione
- Dexamethasone acetate
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Diseases |
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GWAS |
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- Acute anterior uveitis in ankylosing spondylitis ( 32492107)
- Ankylosing spondylitis ( 23749187 30946743)
- Chronic inflammatory diseases (ankylosing spondylitis, Crohn's disease, psoriasis, primary sclerosing cholangitis, ulcerative colitis) (pleiotropy) ( 26974007)
- Crohn's disease ( 23128233)
- Cutaneous psoriasis ( 26626624)
- Fractional exhaled nitric oxide (childhood) ( 24315451)
- Inflammatory skin disease ( 25574825)
- Psoriasis ( 25903422 20953189 23143594)
- Psoriasis vulgaris ( 26626624)
- Psoriatic arthritis ( 26626624)
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Interacting Genes |
14 interacting genes:
ADPRH
ATM
DDX4
KDM1A
MET
NOS2
PAWR
PRMT1
PRMT6
RASA1
SUV39H1
TRIM55
TRIM63
VWA5A
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11 interacting genes:
ACTB
ACTN4
CAV1
PEX5
RAC1
RAC2
SLC9A3R1
SPSB1
SPSB2
SPSB4
SRC
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Entrez ID |
80176 |
4843 |
HPRD ID |
18106 |
01225 |
Ensembl ID |
ENSG00000171621
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ENSG00000007171
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Uniprot IDs |
A0A024R4G8
Q96BD6
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P35228
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PDB IDs |
2JK9
3F2O
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1NSI
2LL6
2NSI
3E7G
3EJ8
3HR4
4CX7
4NOS
5TP6
5XN3
6JWM
6JWN
6KEY
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Enriched GO Terms of Interacting Partners? |
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Tagcloud ? |
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Tagcloud (Difference) ? |
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Tagcloud (Intersection) ? |
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