TNIP3 and BBS12

Data Source:
BioGRID (affinity chromatography technology)

		TNIP3	BBS12
Description		TNFAIP3 interacting protein 3	Bardet-Biedl syndrome 12
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Cytosol	Cilium
	Molecular Function	Protein Binding Polyubiquitin Modification-dependent Protein Binding	Protein Binding ATP Binding
	Biological Process	MyD88-independent Toll-like Receptor Signaling Pathway Inflammatory Response Protein Deubiquitination Toll-like Receptor 4 Signaling Pathway Negative Regulation Of I-kappaB Kinase/NF-kappaB Signaling Positive Regulation Of Transcription By RNA Polymerase II Cellular Response To Lipopolysaccharide	Intraciliary Transport Eating Behavior Photoreceptor Cell Maintenance Negative Regulation Of Fat Cell Differentiation Chaperone-mediated Protein Complex Assembly
Pathways		Ovarian tumor domain proteases	BBSome-mediated cargo-targeting to cilium
Drugs
Diseases			Bardet-Biedl syndrome (BBS)
GWAS		Breast cancer ( 23468962) Multiple sclerosis ( 31604244)	Asthma ( 31959851) Caudate nucleus volume ( 31530798) Itch intensity from mosquito bite ( 28199695) Itch intensity from mosquito bite adjusted by bite size ( 28199695) Metabolite levels ( 23823483) Mosquito bite size ( 28199695) Night sleep phenotypes ( 27126917)
Interacting Genes		27 interacting genes: CCN3 CYSRT1 DAZAP2 FAM161A KPNA3 KRT40 KRTAP10-3 KRTAP10-8 LITAF LZTS2 MAGEA2 MAGEA2B MTUS2 NBPF19 NOTCH2NLA NTAQ1 PIBF1 PLSCR3 TAX1BP1 TCEANC TNFAIP3 TNIP1 TRIM55 TRIM63 TRIM8 UBC ZBTB8A
Entrez ID		79931	166379
HPRD ID		16268	08759
Ensembl ID		ENSG00000050730	ENSG00000181004
Uniprot IDs		Q96KP6	Q6ZW61
PDB IDs
Enriched GO Terms of Interacting Partners?
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