SETD6 and GINS3

Data Source:
BioGRID (biochemical)

		SETD6	GINS3
Description		SET domain containing 6, protein lysine methyltransferase	GINS complex subunit 3
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GO Annotations	Cellular Component	Nucleus Nucleoplasm Cytosol	GINS Complex Nucleoplasm CMG Complex
	Molecular Function	Protein Binding Protein-lysine N-methyltransferase Activity NF-kappaB Binding	Protein Binding
	Biological Process	Peptidyl-lysine Monomethylation Stem Cell Population Maintenance Negative Regulation Of NF-kappaB Transcription Factor Activity Histone Lysine Methylation Stem Cell Differentiation Regulation Of Inflammatory Response	DNA Strand Elongation Involved In DNA Replication Mitotic DNA Replication Initiation
Pathways		PKMTs methylate histone lysines	Unwinding of DNA Unwinding of DNA
Drugs
Diseases
GWAS		Autism spectrum disorder or schizophrenia ( 28540026) Electrocardiogram morphology (amplitude at temporal datapoints) ( 32916098) Oily fish consumption ( 32066663) Pork consumption ( 32066663) Pulse pressure ( 30578418) QT interval ( 29213071) Schizophrenia ( 29483656)	Electrocardiogram morphology (amplitude at temporal datapoints) ( 32916098) Electrocardiographic traits ( 32602732) QT interval ( 19305408) TPE interval (resting) ( 32386560)
Interacting Genes		1 interacting genes: ATXN1	8 interacting genes: CTNNA3 GINS4 KRT80 MEOX2 MYO15B SMARCD1 TRAPPC6A VAC14
Entrez ID		79918	64785
HPRD ID		07956	07842
Ensembl ID		ENSG00000103037	ENSG00000181938
Uniprot IDs		Q8TBK2	A0A0S2Z5L0 A0A0S2Z5L4 A0A0S2Z5P2 Q9BRX5
PDB IDs		3QXY 3RC0	2E9X 2EHO 2Q9Q 6XTX 6XTY
Enriched GO Terms of Interacting Partners?
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