GTDC1 and ZEB2

Data Source:
BioGRID (affinity chromatography technology)

		GTDC1	ZEB2
Description		glycosyltransferase like domain containing 1	zinc finger E-box binding homeobox 2
Image		No pdb structure
GO Annotations	Cellular Component		Chromatin Nucleus Nucleoplasm Nucleolus Cytosol
	Molecular Function		RNA Polymerase II Cis-regulatory Region Sequence-specific DNA Binding DNA-binding Transcription Factor Activity, RNA Polymerase II-specific DNA-binding Transcription Repressor Activity, RNA Polymerase II-specific Protein Binding Phosphatase Regulator Activity Sequence-specific DNA Binding Metal Ion Binding
	Biological Process		Negative Regulation Of Transcription By RNA Polymerase II Regulation Of Transcription By RNA Polymerase II Nervous System Development Positive Regulation Of Melanocyte Differentiation Positive Regulation Of Transcription By RNA Polymerase II Positive Regulation Of Melanin Biosynthetic Process Developmental Pigmentation Anatomical Structure Development Regulation Of Catalytic Activity Melanocyte Migration Regulation Of Melanosome Organization
Pathways
Drugs
Diseases			Mowat-Wilson syndrome
GWAS		Chin dimples ( 27182965) Multiple sclerosis ( 31604244) Obesity-related traits ( 23251661) Voxel-wise structural brain imaging measurements in Alzheimerâ€™s disease ( 31095298 30584014)	Adult body size ( 32376654) Adventurousness ( 30643258) Age-related nuclear cataracts ( 33311586) Childhood absence epilepsy ( 30531953) Chin dimples ( 27182965) Cognitive ability, years of educational attainment or schizophrenia (pleiotropy) ( 31374203) Corneal astigmatism ( 30306274) Coronary artery disease ( 32469254 29212778 26343387) Coronary artery disease (myocardial infarction, percutaneous transluminal coronary angioplasty, coronary artery bypass grafting, angina or chromic ischemic heart disease) ( 28714975) Diastolic blood pressure ( 30224653) Electrocardiogram morphology (amplitude at temporal datapoints) ( 32916098) General risk tolerance (MTAG) ( 30643258) Generalized epilepsy ( 22949513) Hand grip strength ( 29691431) High myopia ( 31816047) Immature fraction of reticulocytes ( 32888494) Mean corpuscular hemoglobin ( 29403010 32888494) Mean corpuscular hemoglobin concentration ( 29403010) Mean corpuscular volume ( 29403010) Medication use (diuretics) ( 31015401) Myocardial infarction ( 26343387) Obesity-related traits ( 23251661) Photic sneeze reflex ( 27182965 30899065) Red blood cell count ( 29403010) Refractive error ( 32231278) Renal cell carcinoma ( 23184150 25826619) Retinal detachment or retinal break ( 31816047) Risk-taking tendency (4-domain principal component model) ( 30643258) Schizophrenia ( 29483656 23974872) Smoking status (ever vs never smokers) ( 30643258) Spherical equivalent or myopia (age of diagnosis) ( 29808027) Triglyceride levels ( 32203549)
Interacting Genes		1 interacting genes: APP	11 interacting genes: APP CBX4 COPS6 CTBP1 CTBP2 SMAD1 SMAD2 SMAD3 SMAD5 SMAD9 UBE2I
Entrez ID		79712	9839
HPRD ID		13615	05780
Ensembl ID		ENSG00000121964	ENSG00000169554
Uniprot IDs		Q4AE62	O60315
PDB IDs			2DA7
Enriched GO Terms of Interacting Partners?
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