ZNF208 and SRY

Data Source:
HPRD (in vitro, two hybrid, in vivo)

		ZNF208	SRY
Description		zinc finger protein 208	sex determining region Y
Image		No pdb structure
GO Annotations	Cellular Component	Nucleus	Chromatin Nucleus Nucleoplasm Cytoplasm Nuclear Speck
	Molecular Function	RNA Polymerase II Cis-regulatory Region Sequence-specific DNA Binding DNA-binding Transcription Activator Activity, RNA Polymerase II-specific Zinc Ion Binding	RNA Polymerase II Cis-regulatory Region Sequence-specific DNA Binding DNA-binding Transcription Factor Activity, RNA Polymerase II-specific DNA Binding Calmodulin Binding Transcription Factor Binding
	Biological Process	Regulation Of Transcription By RNA Polymerase II Positive Regulation Of Transcription By RNA Polymerase II	Negative Regulation Of Transcription By RNA Polymerase II Regulation Of Transcription, DNA-templated Sex Differentiation Anatomical Structure Morphogenesis Positive Regulation Of Gene Expression Cell Differentiation Male Sex Determination Positive Regulation Of Transcription, DNA-templated Positive Regulation Of Transcription By RNA Polymerase II Positive Regulation Of Male Gonad Development
Pathways		Generic Transcription Pathway	Deactivation of the beta-catenin transactivating complex Transcriptional regulation of testis differentiation
Drugs
Diseases			46,XX disorders of sex development (Disorders of gonadal development), including: Ovotesticular DSD; Testicular DSD; Ovarian dysgenesis 46,XY disorders of sex development (Disorders of gonadal development), including: Gonadal agenesis; Complete and partial gonadal dysgenesis; Testis regression; Ovotesticular DSD
GWAS		Body mass index (change over time) ( 25378290) Leukocyte telomere length ( 32109421) Systolic blood pressure ( 30578418)
Interacting Genes		1 interacting genes: SRY	7 interacting genes: AR EP300 HDAC3 KPNB1 SLC9A3R2 SMAD3 ZNF208
Entrez ID		7757	6736
HPRD ID		05998	08364
Ensembl ID		ENSG00000160321	ENSG00000184895
Uniprot IDs		M0QYK4 O43345	A7WPU8 Q05066
PDB IDs			1HRY 1HRZ 1J46 1J47 2GZK 6EDB
Enriched GO Terms of Interacting Partners?
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