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XRCC3 and SNAI1
Data Source:
BioGRID
(two hybrid)
XRCC3
SNAI1
Description
X-ray repair cross complementing 3
snail family transcriptional repressor 1
Image
No pdb structure
GO Annotations
Cellular Component
Chromosome, Telomeric Region
Nucleus
Nucleoplasm
Replication Fork
Cytoplasm
Mitochondrion
Cytosol
Rad51C-XRCC3 Complex
Perinuclear Region Of Cytoplasm
Fibrillar Center
Nucleus
Nucleoplasm
Pericentric Heterochromatin
Cytoplasm
Cytosol
Intracellular Membrane-bounded Organelle
Molecular Function
Four-way Junction DNA Binding
Protein Binding
ATP Binding
DNA-dependent ATPase Activity
Crossover Junction Endodeoxyribonuclease Activity
RNA Polymerase II Transcription Regulatory Region Sequence-specific DNA Binding
RNA Polymerase II Cis-regulatory Region Sequence-specific DNA Binding
DNA-binding Transcription Repressor Activity, RNA Polymerase II-specific
DNA-binding Transcription Factor Activity
Protein Binding
Kinase Binding
Metal Ion Binding
E-box Binding
Sequence-specific Double-stranded DNA Binding
Biological Process
Telomere Maintenance Via Recombination
Double-strand Break Repair Via Homologous Recombination
DNA Repair
DNA Recombination
Cellular Response To DNA Damage Stimulus
Response To Organic Substance
Regulation Of Centrosome Duplication
Interstrand Cross-link Repair
Double-strand Break Repair Via Synthesis-dependent Strand Annealing
Resolution Of Mitotic Recombination Intermediates
Positive Regulation Of Mitotic Cell Cycle Spindle Assembly Checkpoint
T-circle Formation
Telomeric Loop Disassembly
Telomere Maintenance Via Telomere Trimming
Negative Regulation Of Transcription By RNA Polymerase II
Osteoblast Differentiation
Mesoderm Formation
Epithelial To Mesenchymal Transition
Aortic Valve Morphogenesis
Epithelial To Mesenchymal Transition Involved In Endocardial Cushion Formation
Regulation Of Transcription By RNA Polymerase II
Positive Regulation Of Epithelial To Mesenchymal Transition
Negative Regulation Of Vitamin D Biosynthetic Process
Cell Migration
Positive Regulation Of Cell Migration
Hair Follicle Morphogenesis
Negative Regulation Of DNA Damage Response, Signal Transduction By P53 Class Mediator
Positive Regulation Of Transcription, DNA-templated
Roof Of Mouth Development
Cartilage Morphogenesis
Trophoblast Giant Cell Differentiation
Negative Regulation Of Cell Differentiation Involved In Embryonic Placenta Development
Left/right Pattern Formation
Notch Signaling Involved In Heart Development
Heterochromatin Organization
Negative Regulation Of Intrinsic Apoptotic Signaling Pathway In Response To DNA Damage
Regulation Of Bicellular Tight Junction Assembly
Pathways
HDR through Homologous Recombination (HRR)
Resolution of D-loop Structures through Synthesis-Dependent Strand Annealing (SDSA)
Resolution of D-loop Structures through Holliday Junction Intermediates
Homologous DNA Pairing and Strand Exchange
Regulation of PTEN gene transcription
Regulation of PTEN gene transcription
Drugs
Diseases
GWAS
Autism spectrum disorder or schizophrenia (
28540026
)
Bipolar disorder (
31043756
)
Body mass index (
26426971
29273807
)
Schizophrenia (
25056061
29483656
)
Psoriasis (
20953189
)
Interacting Genes
22 interacting genes:
BAP1
BCAS3
CXCL1
FANCG
GREB1
ITIH5
LRATD2
MRC2
OSGIN1
PALB2
PSMC3IP
RAD51
RAD51C
RAD51D
RNF20
SCGB3A1
SERPINB5
SNAI1
SWSAP1
TFF1
ZNHIT3
ZSWIM7
46 interacting genes:
ACTN2
ACTN3
BRMS1
COG6
CTDSP1
CTDSP2
CTDSPL
EFHC1
EP300
EXOSC8
FBXO22
FHL2
GLMN
GOLGA6L9
GSK3B
HOXD4
KRT31
KRT40
KRTAP1-1
KRTAP10-3
LATS2
LSP1
MFHAS1
MID2
MTUS2
NBN
NOTCH1
NOTCH2NLA
OTUB1
PALB2
PAX2
PFDN5
PPIL2
PTEN
PTPN1
RCOR1
TGFB1
TNFAIP3
TRAF2
TRIM23
TRIM50
TRIP6
USP17L2
USP3
USP37
XRCC3
Entrez ID
7517
6615
HPRD ID
07201
05025
Ensembl ID
ENSG00000126215
ENSG00000124216
Uniprot IDs
O43542
Q53XC8
O95863
PDB IDs
2Y48
3W5K
3ZMT
4QLI
Enriched GO Terms of Interacting Partners
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Tagcloud (Difference)
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Tagcloud (Intersection)
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