THRSP and BRMS1

Data Source:
BioGRID (two hybrid)

		THRSP	BRMS1
Description		thyroid hormone responsive	BRMS1 transcriptional repressor and anoikis regulator
Image		No pdb structure
GO Annotations	Cellular Component	Nucleoplasm Cytosol	Nucleus Nucleoplasm Cytoplasm Sin3-type Complex
	Molecular Function	Protein Binding Identical Protein Binding Protein Homodimerization Activity	Protein Binding Histone Deacetylase Binding NF-kappaB Binding
	Biological Process	Lipid Metabolic Process Carnitine Shuttle Response To Bacterium Regulation Of Triglyceride Biosynthetic Process Regulation Of Lipid Biosynthetic Process	Negative Regulation Of Transcription By RNA Polymerase II Apoptotic Process Histone Deacetylation Negative Regulation Of NF-kappaB Transcription Factor Activity Regulation Of Apoptotic Process Negative Regulation Of Transcription, DNA-templated Positive Regulation Of Protein Deacetylation Positive Regulation Of Anoikis
Pathways		Carnitine metabolism	HDACs deacetylate histones Potential therapeutics for SARS
Drugs
Diseases
GWAS		Menarche (age at onset) ( 25231870) Tourette syndrome ( 30818990)	Bipolar disorder ( 21926972 31043756)
Interacting Genes		25 interacting genes: AKT1 AURKA BAG4 BCAR3 BRMS1 ERBB2 FGFR4 FZR1 HMMR IGF1R INCA1 KRAS LSP1 PALB2 PARP1 PIK3CA PTPN1 RB1CC1 SMAD4 STK11 TEPSIN TGFB1 TSG101 WT1 ZMYND12	49 interacting genes: ANGPTL4 APP ARID4A BEX2 BRMS1L CEP70 CSNK2A1 CYTOR DIRAS3 DNAJB1 DNAJB6 E2F1 EEF1A1 EP300 GOLGB1 HDAC1 HDAC2 HDAC3 HDAC4 HDAC5 HDAC6 HSP90AA1 HSPA4 IL13RA2 ING1 KLK9 KPNA5 LRIF1 LYPD3 MCRS1 MRC2 NMI PFDN5 PSMC3IP RBBP4 RBBP7 RBP1 RELA SAP30 SIN3A SMARCE1 SMTN SNAI1 SNX6 SPOP SUDS3 TAF1 THRSP UBE2D1
Entrez ID		7069	25855
HPRD ID		03566	05879
Ensembl ID		ENSG00000151365	ENSG00000174744
Uniprot IDs		Q92748	G5E9I4 Q9HCU9
PDB IDs			2XUS 4AUV
Enriched GO Terms of Interacting Partners?
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