BSG and SLC16A1

Data Source:
HPRD (in vivo, in vitro)

		BSG	SLC16A1
Description		basigin (Ok blood group)	solute carrier family 16 member 1
Image			No pdb structure
GO Annotations	Cellular Component	Golgi Membrane Photoreceptor Outer Segment Photoreceptor Inner Segment Acrosomal Membrane Mitochondrion Endosome Endoplasmic Reticulum Membrane Plasma Membrane Integral Component Of Plasma Membrane Focal Adhesion Membrane Basolateral Plasma Membrane Axon Sarcolemma Melanosome Intracellular Membrane-bounded Organelle Membrane Raft Extracellular Exosome	Centrosome Plasma Membrane Integral Component Of Plasma Membrane Basal Plasma Membrane Membrane Integral Component Of Membrane Basolateral Plasma Membrane Apical Plasma Membrane Lateral Plasma Membrane Cell Junction Intracellular Membrane-bounded Organelle Synapse Extracellular Exosome
	Molecular Function	Virus Receptor Activity Protein Binding Mannose Binding Cadherin Binding Cell-cell Adhesion Mediator Activity	Protein Binding Monocarboxylic Acid Transmembrane Transporter Activity Lactate Transmembrane Transporter Activity Mevalonate Transmembrane Transporter Activity Symporter Activity Identical Protein Binding Carboxylic Acid Transmembrane Transporter Activity Organic Cyclic Compound Binding
	Biological Process	Angiogenesis Pyruvate Metabolic Process Homophilic Cell Adhesion Via Plasma Membrane Adhesion Molecules Cell Surface Receptor Signaling Pathway Axon Guidance Embryo Implantation Extracellular Matrix Disassembly Extracellular Matrix Organization Neutrophil Chemotaxis Odontogenesis Of Dentin-containing Tooth Response To Peptide Hormone Response To Mercury Ion Decidualization Viral Entry Into Host Cell Leukocyte Migration Response To CAMP Dendrite Self-avoidance Protein Localization To Plasma Membrane	Pyruvate Metabolic Process Lipid Metabolic Process Centrosome Cycle Monocarboxylic Acid Transport Mevalonate Transport Response To Food Plasma Membrane Lactate Transport Glucose Homeostasis Regulation Of Insulin Secretion Leukocyte Migration Behavioral Response To Nutrient Cellular Response To Organic Cyclic Compound Transport Across Blood-brain Barrier Carboxylic Acid Transmembrane Transport
Pathways		Degradation of the extracellular matrix Basigin interactions Integrin cell surface interactions Proton-coupled monocarboxylate transport Defective SLC16A1 causes symptomatic deficiency in lactate transport (SDLT) Pyruvate metabolism	Basigin interactions Proton-coupled monocarboxylate transport Defective SLC16A1 causes symptomatic deficiency in lactate transport (SDLT) Pyruvate metabolism
Drugs			Pyruvic acid Mersalyl
Diseases
GWAS		Alzheimer's disease (late onset) ( 28714976)	Macular thickness ( 30535121) Proportion of activated microglia (inferior temporal cortex) ( 30679421) Refractive error ( 32231278)
Interacting Genes		18 interacting genes: ADRB2 AQP6 CAV1 CCR4 CHRM3 CRBN F2RL1 HGS MMP1 PDLIM7 PPIA PPIL2 PPP2R1B SLC16A1 SLC16A13 SLC16A3 SLC2A4 UBC	3 interacting genes: AGTR1 BSG CRBN
Entrez ID		682	6566
HPRD ID		00176	02816
Ensembl ID		ENSG00000172270	ENSG00000155380
Uniprot IDs		P35613 Q54A51	A0A024R0H1 B4DKS0 P53985
PDB IDs		3B5H 3I84 3I85 3QQN 3QR2 4U0Q 5X0T 5XF0
Enriched GO Terms of Interacting Partners?
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