SUMO3 and MORC3

Data Source:
BioGRID (two hybrid)

		SUMO3	MORC3
Description		small ubiquitin like modifier 3	MORC family CW-type zinc finger 3
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GO Annotations	Cellular Component	Kinetochore Nucleus Nucleoplasm Cytoplasm PML Body	Nucleoplasm Nuclear Matrix PML Body
	Molecular Function	Protein Binding Protein Tag Ubiquitin-like Protein Ligase Binding	RNA Binding Protein Binding Zinc Ion Binding Methylated Histone Binding
	Biological Process	Protein Sumoylation Negative Regulation Of DNA Binding Regulation Of Protein Localization To Nucleus	Protein Phosphorylation Cell Aging Post-embryonic Development Viral Process Peptidyl-serine Phosphorylation Negative Regulation Of Fibroblast Proliferation Protein Stabilization Maintenance Of Protein Location In Nucleus
Pathways		SUMO is conjugated to E1 (UBA2:SAE1) SUMO is transferred from E1 to E2 (UBE2I, UBC9) SUMO is proteolytically processed SUMOylation of DNA damage response and repair proteins SUMOylation of transcription factors SUMOylation of transcription cofactors SUMOylation of intracellular receptors SUMOylation of intracellular receptors SUMOylation of chromatin organization proteins SUMOylation of DNA replication proteins SUMOylation of immune response proteins Formation of Incision Complex in GG-NER
Drugs
Diseases
GWAS		Delirium ( 29631748)	Diastolic blood pressure ( 30224653) Height ( 31562340)
Interacting Genes		53 interacting genes: ANXA7 BLM CCNE2 CDKN1A CEBPA CHAF1A CUL3 DAXX EGLN3 FAM221A FOS HIPK2 HOMEZ HSF1 HSF2 JUN KALRN MAPKAPK3 PFDN1 PIAS1 PIAS2 PIAS3 PIAS4 PML RANGAP1 RNF111 RNF8 SAE1 SENP1 SENP2 SENP5 SMN1 SOX10 SOX6 SP100 TDG TDP2 TK1 TP53BP2 TTR UBA2 UBE2I UBE3A UPF2 USP25 USPL1 VIM WWTR1 YAP1 ZBTB33 ZBTB39 ZCCHC12 ZNF496	5 interacting genes: ERCC6 KPNA2 RNF216 SUMO2 UBC
Entrez ID		6612	23515
HPRD ID		03754	10316
Ensembl ID		ENSG00000184900	ENSG00000159256
Uniprot IDs		P55854	B4DHJ4 Q14149 Q4VBZ9
PDB IDs		1U4A 2IO1 2MP2 6K5R 6NNQ	4QQ4 5SVI 5SVX 5SVY 6O1E 6O5W
Enriched GO Terms of Interacting Partners?
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