SLIT3 and MGAT4B

Data Source:
BioGRID (genetic interference)

		SLIT3	MGAT4B
Description		slit guidance ligand 3	alpha-1,3-mannosyl-glycoprotein 4-beta-N-acetylglucosaminyltransferase B
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Extracellular Space Mitochondrion	Golgi Membrane Endoplasmic Reticulum Endoplasmic Reticulum-Golgi Intermediate Compartment Golgi Stack Integral Component Of Membrane
	Molecular Function	Calcium Ion Binding Heparin Binding Roundabout Binding	Protein Binding Acetylglucosaminyltransferase Activity Alpha-1,3-mannosylglycoprotein 4-beta-N-acetylglucosaminyltransferase Activity Metal Ion Binding
	Biological Process	Aortic Valve Morphogenesis Atrioventricular Valve Morphogenesis Axon Guidance Negative Regulation Of Cell Population Proliferation Negative Regulation Of Gene Expression Chemorepulsion Involved In Embryonic Olfactory Bulb Interneuron Precursor Migration Negative Regulation Of Cell Growth Cellular Response To Hormone Stimulus Roundabout Signaling Pathway Axon Extension Involved In Axon Guidance Negative Chemotaxis Response To Cortisol Ventricular Septum Morphogenesis Apoptotic Process Involved In Luteolysis Negative Regulation Of Chemokine-mediated Signaling Pathway	Protein N-linked Glycosylation N-glycan Processing Protein Phosphopantetheinylation
Pathways		Netrin-1 signaling Signaling by ROBO receptors Signaling by ROBO receptors Regulation of commissural axon pathfinding by SLIT and ROBO	Maturation of spike protein N-Glycan antennae elongation
Drugs
Diseases
GWAS		Atrial fibrillation ( 30061737) Body mass index ( 31217584) Circulating leptin levels in high cardiovascular risk ( 31766143) Circulating leptin levels x sex interaction in high cardiovascular risk ( 31766143) Diastolic blood pressure x educational attainment (graduated college) interaction (2df) ( 32372009) Gut microbiota (functional units) ( 27694959) Hallux valgus ( 32131869) Height ( 28552196 20881960 25282103 25429064 31562340) Inflammatory skin disease ( 25574825) Menarche (age at onset) ( 25231870) Non-word reading ( 30741946) Treatment resistant depression ( 30468137)	Blood protein levels ( 30072576 29875488) Major depressive disorder ( 27479909) Plateletcrit ( 32888494)
Interacting Genes		2 interacting genes: CAPN1 ROBO2	2 interacting genes: APPBP2 LRSAM1
Entrez ID		6586	11282
HPRD ID		04775	05190
Ensembl ID		ENSG00000184347	ENSG00000161013
Uniprot IDs		O75094	Q9UQ53
PDB IDs
Enriched GO Terms of Interacting Partners?
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