BMP8B and NSD3

Data Source:
BioGRID (biochemical)

		BMP8B	NSD3
Description		bone morphogenetic protein 8b	nuclear receptor binding SET domain protein 3
Image		No pdb structure
GO Annotations	Cellular Component	Extracellular Space	Chromatin Nucleus Nucleoplasm
	Molecular Function	Cytokine Activity Growth Factor Activity BMP Receptor Binding	Protein Binding Histone-lysine N-methyltransferase Activity Metal Ion Binding Histone Methyltransferase Activity (H3-K36 Specific) Transcription Regulator Activator Activity
	Biological Process	Skeletal System Development Ossification Positive Regulation Of Pathway-restricted SMAD Protein Phosphorylation Cell Differentiation BMP Signaling Pathway Cartilage Development SMAD Protein Signal Transduction	Regulation Of Transcription, DNA-templated Histone H3-K36 Methylation Histone Methylation Positive Regulation Of Transcription, DNA-templated Positive Regulation Of Histone H3-K36 Trimethylation
Pathways			PKMTs methylate histone lysines
Drugs
Diseases
GWAS		Blood protein levels ( 28240269)
Interacting Genes		1 interacting genes: BMP4	42 interacting genes: AKT1 ATM BCAR3 CASP8 CBLC CBX3 CBX5 CDKN2A CHEK2 DAXX DOCK7 ESR1 ETV3 FGFR4 GLIS2 GLYR1 H1-1 H3-5 H3C1 H4C1 HOXC4 MLLT6 MNDA MYC NFIC PAX2 PPM1D RB1CC1 SEPTIN6 SLU7 SOX3 SOX4 SPAG8 STAC3 TCF3 TEAD2 TERT TGFB1 TRIM55 TRIM63 UBE2I ZNF557
Entrez ID		656	54904
HPRD ID		03792	06155
Ensembl ID		ENSG00000116985	ENSG00000147548
Uniprot IDs		P34820	Q9BZ95
PDB IDs			2DAQ 2NCZ 2ND1 4GND 4GNE 4GNF 4GNG 4RXJ 5UPD 6CEN 6G24 6G25 6G27 6G29 6G2B 6G2C 6G2E 6G2F 6G2O 6G3P 6G3T 7CRP 7CRQ 7CRR
Enriched GO Terms of Interacting Partners?
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