MRPL36 and SLC6A3

Data Source:
BioGRID (affinity chromatography technology)

		MRPL36	SLC6A3
Description		mitochondrial ribosomal protein L36	solute carrier family 6 member 3
Image			No pdb structure
GO Annotations	Cellular Component	Mitochondrion Mitochondrial Inner Membrane Mitochondrial Large Ribosomal Subunit Nuclear Body	Cytoplasm Plasma Membrane Integral Component Of Plasma Membrane Cell Surface Integral Component Of Membrane Flotillin Complex Axon Neuronal Cell Body Membrane Presynaptic Membrane Neuron Projection Neuronal Cell Body Membrane Raft Dopaminergic Synapse Integral Component Of Postsynaptic Membrane Integral Component Of Presynaptic Membrane
	Molecular Function	Structural Constituent Of Ribosome Protein Binding	Protease Binding Signaling Receptor Binding Neurotransmitter Transmembrane Transporter Activity Dopamine:sodium Symporter Activity Norepinephrine:sodium Symporter Activity Protein Binding Drug Binding Monoamine Transmembrane Transporter Activity Dopamine Binding Protein-containing Complex Binding Metal Ion Binding Protein N-terminus Binding Protein Phosphatase 2A Binding
	Biological Process	Translation Ribosome Biogenesis Mitochondrial Translational Elongation Mitochondrial Translational Termination	Neurotransmitter Transport Aging Lactation Sensory Perception Of Smell Locomotory Behavior Response To Iron Ion Monoamine Transport Dopamine Transport Norepinephrine Transport Adenohypophysis Development Response To Nicotine Sodium Ion Transmembrane Transport Positive Regulation Of Multicellular Organism Growth Regulation Of Dopamine Metabolic Process Neurotransmitter Biosynthetic Process Response To Cocaine Dopamine Biosynthetic Process Dopamine Catabolic Process Response To Drug Response To Ethanol Dopamine Uptake Involved In Synaptic Transmission Response To CAMP Norepinephrine Uptake Prepulse Inhibition Dopamine Uptake Hyaloid Vascular Plexus Regression
Pathways		Mitochondrial translation initiation Mitochondrial translation elongation Mitochondrial translation elongation Mitochondrial translation termination	Dopamine clearance from the synaptic cleft Na+/Cl- dependent neurotransmitter transporters Defective SLC6A3 causes Parkinsonism-dystonia infantile (PKDYS) Defective SLC6A3 causes Parkinsonism-dystonia infantile (PKDYS)
Drugs			Amphetamine Phentermine Benzatropine Venlafaxine Loxapine Methylphenidate Meperidine Imipramine Duloxetine Amoxapine Mazindol Procaine Trimipramine Modafinil Phenmetrazine Pseudoephedrine Benzphetamine Cocaine Diethylpropion Dopamine Sertraline Sibutramine Chlorpheniramine Diphenylpyraline Nefazodone Bupropion Chloroprocaine Escitalopram Aripiprazole Ephedra sinica root MMDA Midomafetamine Fencamfamin 4-Methoxyamphetamine Dextroamphetamine Metamfetamine Vanoxerine Nomifensine Altropane Mianserin Tesofensine Trodusquemine Armodafinil Desvenlafaxine Dexmethylphenidate Dasotraline Solriamfetol
Diseases
GWAS		Response to TNF inhibitor in rheumatoid arthritis (change in tender 28-joint count) ( 30166627)	Pancreatic cancer ( 25086665)
Interacting Genes		2 interacting genes: CIDEB RRAS	9 interacting genes: DRD2 MTNR1A NEDD4 PICK1 RACK1 SNCA SNTA1 STX1A TGFB1I1
Entrez ID		64979	6531
HPRD ID		14756	00543
Ensembl ID		ENSG00000171421	ENSG00000142319
Uniprot IDs		Q9P0J6	Q01959
PDB IDs		3J7Y 3J9M 5OOL 6I9R 6NU2 6NU3 6VLZ 6VMI 6ZS9 6ZSA 6ZSB 6ZSC 6ZSD 6ZSE 6ZSG
Enriched GO Terms of Interacting Partners?
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