BCL11B and WDR25

Data Source:
BioGRID (affinity chromatography technology)
HPRD (in vivo, in vitro)

		BCL11B	WDR25
Description		BAF chromatin remodeling complex subunit BCL11B	WD repeat domain 25
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Nucleus Neuron Projection
	Molecular Function	RNA Polymerase II Cis-regulatory Region Sequence-specific DNA Binding DNA-binding Transcription Activator Activity, RNA Polymerase II-specific DNA-binding Transcription Factor Activity Protein Binding Metal Ion Binding Sequence-specific Double-stranded DNA Binding	Protein Binding
	Biological Process	Keratinocyte Development Epithelial Cell Morphogenesis Regulation Of Transcription By RNA Polymerase II Negative Regulation Of Cell Population Proliferation Regulation Of Keratinocyte Proliferation Regulation Of Lipid Metabolic Process Striatal Medium Spiny Neuron Differentiation Commitment Of Neuronal Cell To Specific Neuron Type In Forebrain Post-embryonic Camera-type Eye Development T Cell Differentiation In Thymus T Cell Receptor V(D)J Recombination Hematopoietic Stem Cell Migration Odontogenesis Of Dentin-containing Tooth Negative Regulation Of Apoptotic Process Positive T Cell Selection Regulation Of Neuron Differentiation Positive Regulation Of Transcription By RNA Polymerase II Alpha-beta T Cell Differentiation Thymus Development Olfactory Bulb Axon Guidance Lymphoid Lineage Cell Migration Into Thymus
Pathways
Drugs
Diseases
GWAS		Adult body size ( 32376654) Adventurousness ( 30643258) Airway wall thickness ( 25517131) anorexia nervosa, attention-deficit/hyperactivity disorder, autism spectrum disorder, bipolar disorder, major depression, obsessive-compulsive disorder, schizophrenia, or Tourette syndrome (pleiotropy) ( 31835028) Aortic stiffness ( 22068335) Bipolar disorder ( 31043756) Brain morphology (MOSTest) ( 32665545) Corneal curvature ( 22969067) Diastolic blood pressure night-to-day ratio in hypertension ( 29973135) Hematocrit ( 32888494) Hemoglobin ( 32888494) Metabolite levels ( 23823483) Red blood cell count ( 32888494) Schizophrenia ( 28991256 25056061 29483656 30285260) Staphylococcus aureus infection ( 24847357) Systolic blood pressure night-to-day ratio in hypertension ( 29973135)	Menarche (age at onset) ( 27182965 25231870) Refractive error ( 32231278)
Interacting Genes		9 interacting genes: CBX5 MBD3 MTA2 NR2F1 NR2F2 RBBP4 RBBP7 SP1 SUV39H1	31 interacting genes: AKAP8L C19orf54 CNFN CYSRT1 DVL3 FAM168B FHL3 FOXI1 GOLGA6L9 HSF2BP KRT31 KRT34 KRT40 KRTAP12-3 KRTAP15-1 KRTAP3-1 KRTAP6-3 LDOC1 LNX1 MKRN3 NBPF19 NOTCH2NLA NOTCH3 PFDN5 PNMA1 PRDM14 PSME3 TEPSIN TRIM23 UBXN11 ZNF34
Entrez ID		64919	79446
HPRD ID		05950	14649
Ensembl ID		ENSG00000127152	ENSG00000176473
Uniprot IDs		L8B567 L8B7P7 L8B862 L8B8F6 Q9C0K0	A0A384NPW5 Q64LD2
PDB IDs
Enriched GO Terms of Interacting Partners?
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