ST3GAL3 and SCAMP2

Data Source:
BioGRID (two hybrid)
HPRD (two hybrid)

		ST3GAL3	SCAMP2
Description		ST3 beta-galactoside alpha-2,3-sialyltransferase 3	secretory carrier membrane protein 2
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Golgi Membrane Extracellular Region Integral Component Of Membrane Golgi Cisterna Membrane	Golgi Apparatus Integral Component Of Membrane Transport Vesicle Trans-Golgi Network Membrane Intracellular Membrane-bounded Organelle Recycling Endosome Membrane Extracellular Exosome
	Molecular Function	Protein Binding N-acetyllactosaminide Alpha-2,3-sialyltransferase Activity Sialyltransferase Activity	Protein Binding
	Biological Process	Protein Glycosylation O-glycan Processing Keratan Sulfate Biosynthetic Process Sialylation	Post-Golgi Vesicle-mediated Transport Protein Transport
Pathways		Pre-NOTCH Processing in Golgi Keratan sulfate biosynthesis Defective ST3GAL3 causes MCT12 and EIEE15 Sialic acid metabolism Lewis blood group biosynthesis Maturation of protein 3a Maturation of spike protein Maturation of protein 3a Termination of O-glycan biosynthesis
Drugs
Diseases		Nonsyndromic autosomal recessive mental retardation (NS-ARMR)
GWAS		Aging (time to event) ( 21782286) Amyotrophic lateral sclerosis (age of onset) ( 22959728) Attention deficit hyperactivity disorder ( 29325848) Autism spectrum disorder or schizophrenia ( 28540026) Cognitive ability ( 29186694) Cognitive ability (MTAG) ( 29186694) Coronary artery calcified atherosclerotic plaque (130 HU threshold) in type 2 diabetes ( 29221444) General cognitive ability ( 29844566) Household income ( 31844048) Household income (MTAG) ( 31844048) Intelligence (MTAG) ( 29326435) Left-handedness ( 32989287) Monocyte percentage of white cells ( 32888494) Non-lobar intracerebral hemorrhage (MTAG) ( 31430377) Refractive error ( 32231278) Schizophrenia ( 28991256)	Caffeine consumption ( 21490707) Diastolic blood pressure x alcohol consumption interaction (2df test) ( 29912962) Diastolic blood pressure x smoking status (current vs non-current) interaction (2df test) ( 29455858) Diastolic blood pressure x smoking status (ever vs never) interaction (2df test) ( 29455858) Granulocyte percentage of myeloid white cells ( 27863252) Monocyte percentage of white cells ( 32888494 27863252) Multiple sclerosis ( 31604244) Systolic blood pressure x smoking status (current vs non-current) interaction (2df test) ( 29455858) Systolic blood pressure x smoking status (ever vs never) interaction (2df test) ( 29455858)
Interacting Genes		5 interacting genes: ACTG1 RPL8 SCAMP2 TTR ZBTB5	5 interacting genes: ARIH2 SCAMP1 SLC9A7 SNAP23 ST3GAL3
Entrez ID		6487	10066
HPRD ID		05930	06073
Ensembl ID		ENSG00000126091	ENSG00000140497
Uniprot IDs		A0A2R8Y732 Q11203	A0A140VK92 A8K769 O15127
PDB IDs
Enriched GO Terms of Interacting Partners?
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