ABCG4 and NLRX1

Data Source:
BioGRID (affinity chromatography technology)

		ABCG4	NLRX1
Description		ATP binding cassette subfamily G member 4	NLR family member X1
Image		No pdb structure
GO Annotations	Cellular Component	Plasma Membrane Integral Component Of Membrane	Mitochondrion Mitochondrial Outer Membrane Plasma Membrane Cell Junction
	Molecular Function	Protein Binding ATP Binding ATPase Activity ATPase-coupled Transmembrane Transporter Activity Identical Protein Binding Protein Homodimerization Activity Protein Heterodimerization Activity	Protein Binding ATP Binding
	Biological Process	Cholesterol Efflux Transmembrane Transport Cellular Response To Leukemia Inhibitory Factor	Viral Process Negative Regulation Of Type I Interferon Production Negative Regulation Of Interferon-beta Production Negative Regulation Of Interleukin-6 Production Intracellular Signal Transduction Negative Regulation Of RIG-I Signaling Pathway Negative Regulation Of I-kappaB Kinase/NF-kappaB Signaling Innate Immune Response Negative Regulation Of Innate Immune Response Negative Regulation Of Inflammatory Response
Pathways		ABC transporters in lipid homeostasis	DDX58/IFIH1-mediated induction of interferon-alpha/beta Negative regulators of DDX58/IFIH1 signaling
Drugs
Diseases
GWAS		Lymphocyte counts ( 27863252) Monocyte percentage of white cells ( 32888494) Neutrophil percentage of white cells ( 32888494 27863252)	Mean reticulocyte volume ( 32888494)
Interacting Genes		6 interacting genes: ABCG1 GPR152 PLEKHF2 SGTB TMEM50A ZDHHC17	1 interacting genes: SARM1
Entrez ID		64137	79671
HPRD ID		12130	17640
Ensembl ID		ENSG00000172350	ENSG00000160703
Uniprot IDs		Q9H172	Q86UT6
PDB IDs			3UN9
Enriched GO Terms of Interacting Partners?
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