PRDM14 and NDUFB9

Data Source:
BioGRID (affinity chromatography technology, proximity labelling technology)

		PRDM14	NDUFB9
Description		PR/SET domain 14	NADH:ubiquinone oxidoreductase subunit B9
Image		No pdb structure
GO Annotations	Cellular Component	Nucleus Nucleoplasm	Mitochondrion Mitochondrial Inner Membrane Mitochondrial Respiratory Chain Complex I
	Molecular Function	RNA Polymerase II Transcription Regulatory Region Sequence-specific DNA Binding RNA Binding Protein Binding Methyltransferase Activity Chromatin DNA Binding Metal Ion Binding	Protein Binding NADH Dehydrogenase (ubiquinone) Activity
	Biological Process	Negative Regulation Of Transcription By RNA Polymerase II Cell Morphogenesis Cell Fate Specification Inner Cell Mass Cell Fate Commitment Regulation Of Transcription By RNA Polymerase II Germ Cell Development Embryo Implantation Fertilization Regulation Of Gene Expression Germ-line Stem Cell Population Maintenance Histone H3-R26 Methylation Somatic Stem Cell Population Maintenance Negative Regulation Of Fibroblast Growth Factor Receptor Signaling Pathway Regulation Of DNA Methylation Homeostasis Of Number Of Cells Within A Tissue Inactivation Of Paternal X Chromosome Positive Regulation Of Flagellated Sperm Motility Positive Regulation Of Stem Cell Population Maintenance	Mitochondrial Electron Transport, NADH To Ubiquinone Sensory Perception Of Sound Mitochondrial Respiratory Chain Complex I Assembly
Pathways		Transcriptional regulation of pluripotent stem cells	Respiratory electron transport Complex I biogenesis
Drugs			NADH
Diseases
GWAS		Schizophrenia ( 30285260) Testicular germ cell tumor ( 28604728 28604732 23666240)
Interacting Genes		67 interacting genes: ABI2 AKAP9 AQP1 ATPAF2 BAG4 BAHD1 BCAR3 BEX2 CARD10 CASP8 CBFA2T2 CDCA7L CHEK2 CREB5 DGCR6 DMRT3 EED EIF4E2 ENKD1 ERBB2 EZH2 FAM83A GAS8 GEM GLYCTK GPATCH2L HEXIM2 HOXB5 HOXC8 HSPB7 ID3 IDH1 KANK2 LNX1 MIA3 MRPL32 MYPOP PALB2 PATZ1 PAX2 PLEKHF2 PPP1R32 PRKAB2 PRPF31 PSMA1 PTPRJ RAD51D RBM10 RCOR3 RUNX1T1 RUSC1 SCNM1 SNRPC SUZ12 TCAF1 TEAD4 TEKT4 TLE5 TRIM41 TSGA10 TTC32 TXK USP2 WDR25 ZNF250 ZNF587 ZNF835	11 interacting genes: ELP1 FEZ1 GDF9 HAP1 IMMT MAGEA11 MEF2A RBBP6 SH3GL3 UBC XRN1
Entrez ID		63978	4715
HPRD ID		11457	03264
Ensembl ID		ENSG00000147596	ENSG00000147684
Uniprot IDs		Q9GZV8	E9PH64 Q9Y6M9
PDB IDs			5XTC 5XTD 5XTH 5XTI
Enriched GO Terms of Interacting Partners?
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