BCS1L and MRPS12

Data Source:
BioGRID (affinity chromatography technology)

		BCS1L	MRPS12
Description		BCS1 homolog, ubiquinol-cytochrome c reductase complex chaperone	mitochondrial ribosomal protein S12
Image		No pdb structure
GO Annotations	Cellular Component	Mitochondrion Mitochondrial Inner Membrane Mitochondrial Respiratory Chain Complex III Integral Component Of Membrane	Mitochondrial Inner Membrane Mitochondrial Ribosome Mitochondrial Small Ribosomal Subunit Ribosome
	Molecular Function	Protein Binding ATP Binding ATPase Activity	RNA Binding Structural Constituent Of Ribosome Protein Binding
	Biological Process	Mitochondrion Organization Protein Insertion Into Mitochondrial Inner Membrane From Matrix Mitochondrial Respiratory Chain Complex I Assembly Mitochondrial Cytochrome C Oxidase Assembly Mitochondrial Respiratory Chain Complex III Assembly	Translation Mitochondrial Translation Mitochondrial Translational Elongation Mitochondrial Translational Termination
Pathways		Mitochondrial protein import	Mitochondrial translation initiation Mitochondrial translation elongation Mitochondrial translation elongation Mitochondrial translation termination
Drugs
Diseases		Bjornstad syndrome Mitochondrial respiratory chain deficiencies (MRCD), including: Mitochondrial complex I deficiency (MT-C1D); Complex II deficiency (MT-C2D); Complex III deficiency (MT-C3D); Complex IV deficiency (MT-C4D); Complex V deficiency (MT-ATPSD); Leigh syndrome (LS); Kearns-Sayre Syndrome (KSS); LCHD deficiency (LCHD); Leber Hereditary Optic Neuropathy (LHON); Myoclonic Epilepsy and Ragged-Red Fiber Disease (MERRF); NARP; MELAS; ACAD9 deficiency; HADH deficiency; HIBCH deficiency; GRACILE syndrome
GWAS		Male-pattern baldness ( 28196072)
Interacting Genes		3 interacting genes: DDX24 DNAJA1 MTDH	5 interacting genes: CRMP1 ERG28 LRIF1 SPINK7 UNC119
Entrez ID		617	6183
HPRD ID		04708	04316
Ensembl ID		ENSG00000074582	ENSG00000128626
Uniprot IDs		A0A024R445 A8JZZ8 Q9Y276	A0A024R0H2 O15235
PDB IDs			3J9M 6NU2 6NU3 6RW4 6RW5 6VLZ 6VMI 6ZS9 6ZSA 6ZSB 6ZSC 6ZSD 6ZSE 6ZSG
Enriched GO Terms of Interacting Partners?
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