BCS1L and RPE

Data Source:
BioGRID (proximity labelling technology)

		BCS1L	RPE
Description		BCS1 homolog, ubiquinol-cytochrome c reductase complex chaperone	ribulose-5-phosphate-3-epimerase
Image		No pdb structure
GO Annotations	Cellular Component	Mitochondrion Mitochondrial Inner Membrane Mitochondrial Respiratory Chain Complex III Integral Component Of Membrane	Cytosol Extracellular Exosome
	Molecular Function	Protein Binding ATP Binding ATPase Activity	Ribulose-phosphate 3-epimerase Activity Protein Binding Identical Protein Binding Protein Homodimerization Activity Metal Ion Binding
	Biological Process	Mitochondrion Organization Protein Insertion Into Mitochondrial Inner Membrane From Matrix Mitochondrial Respiratory Chain Complex I Assembly Mitochondrial Cytochrome C Oxidase Assembly Mitochondrial Respiratory Chain Complex III Assembly	Carbohydrate Metabolic Process Pentose-phosphate Shunt Pentose-phosphate Shunt, Non-oxidative Branch Pentose Catabolic Process Cellular Carbohydrate Metabolic Process
Pathways		Mitochondrial protein import	Pentose phosphate pathway
Drugs
Diseases		Bjornstad syndrome Mitochondrial respiratory chain deficiencies (MRCD), including: Mitochondrial complex I deficiency (MT-C1D); Complex II deficiency (MT-C2D); Complex III deficiency (MT-C3D); Complex IV deficiency (MT-C4D); Complex V deficiency (MT-ATPSD); Leigh syndrome (LS); Kearns-Sayre Syndrome (KSS); LCHD deficiency (LCHD); Leber Hereditary Optic Neuropathy (LHON); Myoclonic Epilepsy and Ragged-Red Fiber Disease (MERRF); NARP; MELAS; ACAD9 deficiency; HADH deficiency; HIBCH deficiency; GRACILE syndrome
GWAS		Male-pattern baldness ( 28196072)	Serum metabolite levels ( 23093944)
Interacting Genes		3 interacting genes: DDX24 DNAJA1 MTDH	2 interacting genes: EXOSC10 PLEKHF2
Entrez ID		617	6120
HPRD ID		04708	01608
Ensembl ID		ENSG00000074582	ENSG00000197713
Uniprot IDs		A0A024R445 A8JZZ8 Q9Y276	C9IZU8 C9J9T0 Q96AT9
PDB IDs			3OVP 3OVQ 3OVR 3QC3
Enriched GO Terms of Interacting Partners?
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