BCS1L and WDFY1

Data Source:
BioGRID (biochemical)

		BCS1L	WDFY1
Description		BCS1 homolog, ubiquinol-cytochrome c reductase complex chaperone	WD repeat and FYVE domain containing 1
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Mitochondrion Mitochondrial Inner Membrane Mitochondrial Respiratory Chain Complex III Integral Component Of Membrane	Nucleus Early Endosome Cytosol
	Molecular Function	Protein Binding ATP Binding ATPase Activity	Protein Binding 1-phosphatidylinositol Binding Zinc Ion Binding
	Biological Process	Mitochondrion Organization Protein Insertion Into Mitochondrial Inner Membrane From Matrix Mitochondrial Respiratory Chain Complex I Assembly Mitochondrial Cytochrome C Oxidase Assembly Mitochondrial Respiratory Chain Complex III Assembly	Positive Regulation Of Toll-like Receptor 3 Signaling Pathway Positive Regulation Of Toll-like Receptor 4 Signaling Pathway
Pathways		Mitochondrial protein import
Drugs
Diseases		Bjornstad syndrome Mitochondrial respiratory chain deficiencies (MRCD), including: Mitochondrial complex I deficiency (MT-C1D); Complex II deficiency (MT-C2D); Complex III deficiency (MT-C3D); Complex IV deficiency (MT-C4D); Complex V deficiency (MT-ATPSD); Leigh syndrome (LS); Kearns-Sayre Syndrome (KSS); LCHD deficiency (LCHD); Leber Hereditary Optic Neuropathy (LHON); Myoclonic Epilepsy and Ragged-Red Fiber Disease (MERRF); NARP; MELAS; ACAD9 deficiency; HADH deficiency; HIBCH deficiency; GRACILE syndrome
GWAS		Male-pattern baldness ( 28196072)	Night sleep phenotypes ( 27126917)
Interacting Genes		3 interacting genes: DDX24 DNAJA1 MTDH
Entrez ID		617	57590
HPRD ID		04708	15663
Ensembl ID		ENSG00000074582	ENSG00000085449
Uniprot IDs		A0A024R445 A8JZZ8 Q9Y276	A0A024R488 Q8IWB7 Q9H8N9
PDB IDs
Enriched GO Terms of Interacting Partners?
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