BCS1L and AOX1

Data Source:
BioGRID (two hybrid)

		BCS1L	AOX1
Description		BCS1 homolog, ubiquinol-cytochrome c reductase complex chaperone	aldehyde oxidase 1
Image		No pdb structure
GO Annotations	Cellular Component	Mitochondrion Mitochondrial Inner Membrane Mitochondrial Respiratory Chain Complex III Integral Component Of Membrane	Cytosol Extracellular Exosome
	Molecular Function	Protein Binding ATP Binding ATPase Activity	Aldehyde Oxidase Activity Iron Ion Binding Electron Transfer Activity Oxidoreductase Activity Identical Protein Binding Protein Homodimerization Activity Molybdopterin Cofactor Binding Flavin Adenine Dinucleotide Binding NAD Binding 2 Iron, 2 Sulfur Cluster Binding FAD Binding Geranial:oxygen Oxidoreductase Activity Heptaldehyde:oxygen Oxidoreductase Activity
	Biological Process	Mitochondrion Organization Protein Insertion Into Mitochondrial Inner Membrane From Matrix Mitochondrial Respiratory Chain Complex I Assembly Mitochondrial Cytochrome C Oxidase Assembly Mitochondrial Respiratory Chain Complex III Assembly	Drug Metabolic Process Electron Transport Chain Vitamin B6 Metabolic Process
Pathways		Mitochondrial protein import	Vitamins B6 activation to pyridoxal phosphate
Drugs			Cyclobenzaprine Eniluracil
Diseases		Bjornstad syndrome Mitochondrial respiratory chain deficiencies (MRCD), including: Mitochondrial complex I deficiency (MT-C1D); Complex II deficiency (MT-C2D); Complex III deficiency (MT-C3D); Complex IV deficiency (MT-C4D); Complex V deficiency (MT-ATPSD); Leigh syndrome (LS); Kearns-Sayre Syndrome (KSS); LCHD deficiency (LCHD); Leber Hereditary Optic Neuropathy (LHON); Myoclonic Epilepsy and Ragged-Red Fiber Disease (MERRF); NARP; MELAS; ACAD9 deficiency; HADH deficiency; HIBCH deficiency; GRACILE syndrome	Xanthinuria
GWAS		Male-pattern baldness ( 28196072)	Hip circumference adjusted for BMI ( 28552196) Intelligence ( 22449649) Late-onset Alzheimer's disease ( 27770636)
Interacting Genes		3 interacting genes: DDX24 DNAJA1 MTDH	6 interacting genes: ABCA1 CRKL ERRFI1 GK RBL1 RCHY1
Entrez ID		617	316
HPRD ID		04708	07537
Ensembl ID		ENSG00000074582	ENSG00000138356
Uniprot IDs		A0A024R445 A8JZZ8 Q9Y276	Q06278
PDB IDs			4UHW 4UHX 5EPG 6Q6Q
Enriched GO Terms of Interacting Partners?
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