RPL34 and DAPK3

Data Source:
BioGRID (two hybrid)

		RPL34	DAPK3
Description		ribosomal protein L34	death associated protein kinase 3
Image
GO Annotations	Cellular Component	Endoplasmic Reticulum Cytosol Cytosolic Large Ribosomal Subunit Extracellular Exosome	Nucleus Nucleoplasm Cytoplasm Actin Filament PML Body Membrane Raft
	Molecular Function	RNA Binding Structural Constituent Of Ribosome Protein Binding Cadherin Binding	Protein Serine/threonine Kinase Activity Protein Binding ATP Binding Protein C-terminus Binding CAMP Response Element Binding Protein Binding Small GTPase Binding Identical Protein Binding Protein Homodimerization Activity Leucine Zipper Domain Binding Protein Serine Kinase Activity Protein Threonine Kinase Activity
	Biological Process	Nuclear-transcribed MRNA Catabolic Process, Nonsense-mediated Decay Translation Translational Initiation SRP-dependent Cotranslational Protein Targeting To Membrane Viral Transcription	Chromatin Organization Regulation Of Transcription, DNA-templated Protein Phosphorylation Apoptotic Process Regulation Of Smooth Muscle Contraction Regulation Of Mitotic Nuclear Division Regulation Of Mitotic Cell Cycle Regulation Of Cell Shape Regulation Of Autophagy Negative Regulation Of Translation Neuron Differentiation Positive Regulation Of Cell Migration Intracellular Signal Transduction Regulation Of Apoptotic Process Positive Regulation Of Apoptotic Process Regulation Of Myosin II Filament Organization Protein Autophosphorylation Regulation Of Focal Adhesion Assembly Cellular Response To Interferon-gamma Positive Regulation Of Canonical Wnt Signaling Pathway Apoptotic Signaling Pathway Regulation Of Cell Motility Regulation Of Actin Cytoskeleton Reorganization Positive Regulation Of Extrinsic Apoptotic Signaling Pathway In Absence Of Ligand
Pathways		L13a-mediated translational silencing of Ceruloplasmin expression Peptide chain elongation SRP-dependent cotranslational protein targeting to membrane SRP-dependent cotranslational protein targeting to membrane Viral mRNA Translation Selenocysteine synthesis Major pathway of rRNA processing in the nucleolus and cytosol Formation of a pool of free 40S subunits GTP hydrolysis and joining of the 60S ribosomal subunit Eukaryotic Translation Termination Regulation of expression of SLITs and ROBOs Response of EIF2AK4 (GCN2) to amino acid deficiency Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC) Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)	Caspase activation via Dependence Receptors in the absence of ligand
Drugs			2-tert-butyl-9-fluoro-1,6-dihydrobenzo[h]imidazo[4,5-f]isoquinolin-7-one 4-(6-{[(1R)-1-(hydroxymethyl)propyl]amino}imidazo[1,2-b]pyridazin-3-yl)benzoic acid (4R)-7,8-dichloro-1',9-dimethyl-1-oxo-1,2,4,9-tetrahydrospiro[beta-carboline-3,4'-piperidine]-4-carbonitrile Fostamatinib
Diseases
GWAS		Apolipoprotein A1 levels ( 32203549) Blond vs. brown/black hair color ( 30531825) Height ( 25282103)	Age-related macular degeneration ( 23326517) Expressive vocabulary in infants ( 25226531)
Interacting Genes		7 interacting genes: APP CDK4 CDK5 DAPK3 MAX PTEN SRPK2	15 interacting genes: AATF AK3 ATF4 CDKN1A CHEK2 DAXX GRB14 MDM2 MET NEDD4L PAWR PRKCZ RPL34 TCP10L TP53
Entrez ID		6164	1613
HPRD ID		17996	04478
Ensembl ID		ENSG00000109475	ENSG00000167657
Uniprot IDs		A1LUY1 P49207	B3KNJ3 O43293
PDB IDs		4UG0 4V6X 5AJ0 5LKS 5T2C 6EK0 6IP5 6IP6 6IP8 6LQM 6LSR 6LSS 6LU8 6OLE 6OLF 6OLG 6OLI 6OLZ 6OM0 6OM7 6QZP 6W6L 6XA1 6Y0G 6Y2L 6Y57 6Y6X 6Z6L 6Z6M 6Z6N 6ZM7 6ZME 6ZMI 6ZMO	1YRP 2J90 3BHY 3BQR 5A6N 5A6O 5VJA
Enriched GO Terms of Interacting Partners?
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