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NKX3-2 and GRPEL1
Data Source:
BioGRID
(genetic interference)
NKX3-2
GRPEL1
Description
NK3 homeobox 2
GrpE like 1, mitochondrial
Image
No pdb structure
No pdb structure
GO Annotations
Cellular Component
Chromatin
Nucleus
PAM Complex, Tim23 Associated Import Motor
Nucleoplasm
Mitochondrion
Mitochondrial Matrix
Molecular Function
RNA Polymerase II Cis-regulatory Region Sequence-specific DNA Binding
DNA-binding Transcription Factor Activity, RNA Polymerase II-specific
DNA-binding Transcription Repressor Activity, RNA Polymerase II-specific
Protein Binding
Sequence-specific Double-stranded DNA Binding
Adenyl-nucleotide Exchange Factor Activity
Protein Binding
Identical Protein Binding
Protein Homodimerization Activity
Unfolded Protein Binding
Chaperone Binding
Biological Process
Negative Regulation Of Transcription By RNA Polymerase II
Skeletal System Development
Regulation Of Transcription By RNA Polymerase II
Transcription By RNA Polymerase II
Determination Of Left/right Symmetry
Cell Differentiation
Pancreas Development
Negative Regulation Of Chondrocyte Differentiation
Middle Ear Morphogenesis
Negative Regulation Of Apoptotic Process
Spleen Development
Animal Organ Formation
Skeletal System Morphogenesis
Embryonic Skeletal System Development
Intestinal Epithelial Cell Development
Protein Folding
Protein Import Into Mitochondrial Matrix
Regulation Of Catalytic Activity
Pathways
Regulation of RUNX2 expression and activity
Mitochondrial protein import
Drugs
Diseases
Spondylo-megaepiphyseal-metaphyseal dysplasia
GWAS
Metabolite levels (
23823483
)
Periodontal disease-related phenotype (Socransky) (
24347629
)
Eosinophil percentage of white cells (
32888494
)
Interacting Genes
4 interacting genes:
HDAC1
POU6F2
SMAD1
SMAD4
6 interacting genes:
CCDC57
ERCC6
GALT
POLR1C
SPG21
WBP2
Entrez ID
579
80273
HPRD ID
09075
07550
Ensembl ID
ENSG00000109705
ENSG00000109519
Uniprot IDs
P78367
Q9HAV7
PDB IDs
Enriched GO Terms of Interacting Partners
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Tagcloud
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Tagcloud (Difference)
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Tagcloud (Intersection)
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